Hofstra North Shore-LIJ School of Medicine, Cushing Neuroscience Institutes, Brain and Spine Specialists, North Shore-Long Island Jewish Health System, 270-05 76th Avenue, New Hyde Park, NY 11040, United States.
Epilepsy Res. 2012 Feb;98(2-3):260-3. doi: 10.1016/j.eplepsyres.2011.09.010. Epub 2011 Oct 19.
The outcomes of adult epilepsy patients prescribed lacosamide for additional seizure control. Responders were defined as having at least a 50% decrease in seizure frequency Sixty-seven patients were evaluated. Forty-six out of 67 patients (69%) were responders. Twelve of 14 patients not taking sodium channel-acting AEDs were responders (86%) and 34/53 patients taking sodium channel-acting AEDs were responders (64%) (difference not significant).
接受拉科酰胺治疗以进一步控制癫痫发作的成年癫痫患者的结局。应答者定义为癫痫发作频率至少降低 50%。共评估了 67 例患者。67 例患者中有 46 例（69%）为应答者。未服用钠通道作用 AED 的 14 例患者中有 12 例（86%）为应答者，而服用钠通道作用 AED 的 53 例患者中有 34 例（64%）为应答者（差异无统计学意义）。
