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颈椎后纵韧带骨化症手术并发症的系统评价

A systematic review of complications in cervical spine surgery for ossification of the posterior longitudinal ligament.

机构信息

Department of Orthopedic Surgery, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, 1665 Kongjiang Rd, Shanghai 200092, China.

出版信息

Spine J. 2011 Nov;11(11):1049-57. doi: 10.1016/j.spinee.2011.09.008. Epub 2011 Oct 20.

Abstract

BACKGROUND CONTEXT

Surgical management of ossification of the posterior longitudinal ligament (OPLL) is associated with complications. However, surgical complications for OPLL have not been clearly documented.

PURPOSE

To review and summarize the incidence of surgical complications of OPLL in the cervical spine and evaluate the impact of surgical approach (anterior or posterior), year of study publication, follow-up duration, and the surgical outcome on complication incidence.

STUDY DESIGN

Systematic review.

METHODS

An English literature review was conducted especially on surgical complications of cervical OPLL. The incidence of complications was statistically summarized, with its correlation to surgical approaches, year of study publications, follow-up duration, and the surgical outcome was statistically evaluated.

RESULTS

Twenty-seven retrospective studies, including a total of 1,558 patients, were reviewed. The overall incidence of surgical complications of cervical OPLL was 21.8%. Neurologic deficit (8.3%, overall rate), cerebrospinal fluid leakage (CFL) (5.1%), axial pain (3.5%), and implant complications (3.5%) were relatively common. The incidence of complications for posterior approach was not statistically different from those for anterior procedures. However, with regard to individual complication, C5 palsy and axial pain occurred more frequently in patients approached posteriorly, whereas CFL, implant complications, hoarseness, dysphagia, and dyspnea appeared more common in anterior cases.

CONCLUSIONS

There is a relatively high incidence of surgical complications for cervical OPLL compared with other cervical degeneration diseases. It is, therefore, necessary for surgeons to take into consideration the risk of surgical complications when communicating with patients for decision making and to alert complications during or after surgical procedures.

摘要

背景

颈椎后纵韧带骨化症(ossification of the posterior longitudinal ligament,OPLL)的手术治疗存在相关并发症。然而,OPLL 的手术并发症尚未得到明确记载。

目的

回顾和总结颈椎 OPLL 手术并发症的发生率,并评估手术入路(前路或后路)、研究发表年份、随访时间以及手术结果对并发症发生率的影响。

研究设计

系统回顾。

方法

专门对颈椎 OPLL 的手术并发症进行了英文文献回顾。对并发症的发生率进行了统计学总结,并对其与手术入路、研究发表年份、随访时间和手术结果的相关性进行了统计学评估。

结果

共回顾了 27 项回顾性研究,总计纳入 1558 例患者。颈椎 OPLL 手术并发症的总体发生率为 21.8%。神经功能缺损(8.3%,总发生率)、脑脊液漏(CFL)(5.1%)、轴性疼痛(3.5%)和植入物并发症(3.5%)较为常见。后路手术的并发症发生率与前路手术无统计学差异。然而,对于个别并发症,后路手术患者更易发生 C5 神经根麻痹和轴性疼痛,而前路手术患者更易发生 CFL、植入物并发症、声音嘶哑、吞咽困难和呼吸困难。

结论

与其他颈椎退行性疾病相比,颈椎 OPLL 的手术并发症发生率相对较高。因此,外科医生在与患者沟通决策时需要考虑手术并发症的风险,并在手术过程中或之后警惕并发症的发生。

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