• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

因钴胺素缺乏导致孤立性血小板减少症的病例报告。

Case of isolated thrombocytopenia due to cobalamin deficiency.

机构信息

Duzce University Medical Faculty, Duzce, Turkey.

出版信息

Int J Hematol. 2011 Nov;94(5):488-90. doi: 10.1007/s12185-011-0946-0. Epub 2011 Oct 21.

DOI:10.1007/s12185-011-0946-0
PMID:22015492
Abstract

The most common form of isolated thrombocytopenia is idiopathic thrombocytopenic purpura (ITP) in childhood. Hence, pediatricians consider a possible diagnosis of ITP in patients with isolated thrombocytopenia who are admitted to hospital with complaints of skin findings such as petechiae, purpura, and ecchymosis. It is well known that cobalamin deficiency may also cause thrombocytopenia together with anemia and leukopenia in children. However, isolated thrombocytopenia due to cobalamin deficiency has rarely been reported in literature. In this case report, we present a 7-year-old female patient with isolated thrombocytopenia that was improved by cyanocobalamin therapy.

摘要

最常见的孤立性血小板减少症形式是儿童特发性血小板减少性紫癜(ITP)。因此,儿科医生会考虑对因皮肤瘀点、瘀斑和瘀斑等症状住院的孤立性血小板减少症患者进行 ITP 的可能诊断。众所周知,维生素 B12 缺乏症也可能导致儿童出现血小板减少症,同时伴有贫血和白细胞减少症。然而,文献中很少有报道维生素 B12 缺乏症引起的孤立性血小板减少症。在本病例报告中,我们介绍了一名 7 岁女性患者,其孤立性血小板减少症经氰钴胺治疗后得到改善。

相似文献

1
Case of isolated thrombocytopenia due to cobalamin deficiency.因钴胺素缺乏导致孤立性血小板减少症的病例报告。
Int J Hematol. 2011 Nov;94(5):488-90. doi: 10.1007/s12185-011-0946-0. Epub 2011 Oct 21.
2
Is induction of platelet recovery related to correction of cobalamin deficiency due to Helicobacter pylori eradication in ITP?血小板恢复的诱导是否与根除幽门螺杆菌纠正免疫性血小板减少症(ITP)中的钴胺素缺乏有关?
Am J Hematol. 2005 Oct;80(2):168. doi: 10.1002/ajh.20407.
3
Treatment of vitamin b(12)-deficiency anemia: oral versus parenteral therapy.维生素B12缺乏性贫血的治疗:口服疗法与肠胃外疗法对比
Ann Pharmacother. 2002 Jul-Aug;36(7-8):1268-72. doi: 10.1345/aph.1A122.
4
[Childhood idiopathic thrombocytopenic purpura (the results of 20-year experience)].[儿童特发性血小板减少性紫癜(20年经验结果)]
Georgian Med News. 2009 Sep(174):50-5.
5
Post-Partum Thrombotic Thrombocytopenic Purpura (TTP) in a Patient with known Idiopathic (Immune) Thrombocytopenic Purpura: a case report and review of the literature.一名已知患有特发性(免疫性)血小板减少性紫癜的患者发生产后血栓性血小板减少性紫癜:病例报告及文献综述
J Med Case Rep. 2018 Jun 1;12(1):147. doi: 10.1186/s13256-018-1692-1.
6
[Idiopathic thrombocytopenic purpura in children].[儿童特发性血小板减少性紫癜]
Med Pregl. 1998 Mar-Apr;51(3-4):127-34.
7
Pseudo-Thrombotic Thrombocytopenic Purpura due to Severe Vitamin B12 Deficiency.严重维生素B12缺乏所致的假性血栓性血小板减少性紫癜
J La State Med Soc. 2016 Nov-Dec;168(6):196-200. Epub 2016 Dec 15.
8
Immune thrombocytopenia secondary to tuberculosis: a case and review of literature.结核继发免疫性血小板减少症:1例病例及文献复习
Int J Tuberc Lung Dis. 2017 Apr 1;21(4):466-470. doi: 10.5588/ijtld.16.0515.
9
Immune thrombocytopenic purpura presenting in a patient after renal transplant for diabetic nephropathy.一名因糖尿病肾病接受肾移植的患者出现免疫性血小板减少性紫癜。
BMC Nephrol. 2018 Mar 20;19(1):69. doi: 10.1186/s12882-018-0868-7.
10
Immune thrombocytopenic purpura in a liver transplant patient.肝移植患者的免疫性血小板减少性紫癜
Exp Clin Transplant. 2014 Mar;12 Suppl 1:175-7.

引用本文的文献

1
Vitamin B12 Deficiency, a Rare Cause of Isolated Thrombocytopenia in Adults.维生素B12缺乏症,成人孤立性血小板减少症的罕见病因。
Cureus. 2023 Aug 26;15(8):e44162. doi: 10.7759/cureus.44162. eCollection 2023 Aug.
2
Immune Thrombocytopenia Secondary to COVID-19 in a Vitamin B12-Deficient Patient: A Diagnostic Dilemma and Therapeutic Challenge.一名维生素B12缺乏患者继发于COVID-19的免疫性血小板减少症:诊断困境与治疗挑战
Cureus. 2023 Jun 9;15(6):e40199. doi: 10.7759/cureus.40199. eCollection 2023 Jun.

本文引用的文献

1
Severe vitamin B-12 deficiency in a child mimicking thrombotic thrombocytopenic purpura.
Pediatr Blood Cancer. 2009 Mar;52(3):420-2. doi: 10.1002/pbc.21788.
2
A child with vitamin B12 deficiency presenting with pancytopenia and hyperpigmentation.一名患有维生素B12缺乏症的儿童,表现为全血细胞减少和色素沉着。
J Pediatr Hematol Oncol. 2004 Dec;26(12):834-6.
3
Platelet physiology and thrombosis.血小板生理学与血栓形成
Thromb Res. 2004;114(5-6):447-53. doi: 10.1016/j.thromres.2004.07.020.
4
Vitamin B12 (cobalamin) deficiency in elderly patients.老年患者维生素B12(钴胺素)缺乏症
CMAJ. 2004 Aug 3;171(3):251-9. doi: 10.1503/cmaj.1031155.
5
Vitamin B12 deficiency.维生素B12缺乏症。
Am Fam Physician. 2003 Mar 1;67(5):979-86.
6
Immune thrombocytopenic purpura.免疫性血小板减少性紫癜
N Engl J Med. 2002 Mar 28;346(13):995-1008. doi: 10.1056/NEJMra010501.
7
Hyperhomocysteinemia and elevated methylmalonic acid indicate a high prevalence of cobalamin deficiency in Asian Indians.高同型半胱氨酸血症和甲基丙二酸水平升高表明亚洲印度人维生素B12缺乏症的患病率很高。
Am J Clin Nutr. 2001 Aug;74(2):233-41. doi: 10.1093/ajcn/74.2.233.
8
Vitamin B12 deficiency in children and adolescents.儿童和青少年的维生素B12缺乏症
J Pediatr. 2001 Jan;138(1):10-7. doi: 10.1067/mpd.2001.112160.
9
Sensitivity of serum methylmalonic acid and total homocysteine determinations for diagnosing cobalamin and folate deficiencies.血清甲基丙二酸和总同型半胱氨酸测定对诊断钴胺素和叶酸缺乏症的敏感性。
Am J Med. 1994 Mar;96(3):239-46. doi: 10.1016/0002-9343(94)90149-x.
10
Vitamin B-12 deficiency and malabsorption are highly prevalent in rural Mexican communities.维生素B-12缺乏和吸收不良在墨西哥农村社区极为普遍。
Am J Clin Nutr. 1995 Nov;62(5):1013-9. doi: 10.1093/ajcn/62.5.1013.