Kuz'mitskiĭ B B, Golubeva M B, Konoplia N A, Kovganko N V, Akhrem A A
Farmakol Toksikol. 1990 May-Jun;53(3):20-2.
It was shown that a phytosteroid ecdisterone which is the principle of a new tonic drug ecdisten in doses of 5-20 mg/kg is able to stimulate the primary immune reaction slightly effecting the indices of T-cell immunity activity and phagocyte functions. On increasing ecdisterone dose to 50 mg/kg inhibition of the number of antibody cells in the mouse spleen was marked.
结果表明,作为新型滋补药物蜕皮甾酮主要成分的植物甾醇蜕皮甾酮,在剂量为5-20毫克/千克时,能够轻微刺激初次免疫反应,对T细胞免疫活性指标和吞噬细胞功能影响不大。当蜕皮甾酮剂量增加到50毫克/千克时,小鼠脾脏中抗体细胞数量明显受到抑制。