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[New possibilities in searching for immunomodulators among compounds with a steroid structure].

作者信息

Kuz'mitskiĭ B B, Golubeva M B, Konoplia N A, Kovganko N V, Akhrem A A

出版信息

Farmakol Toksikol. 1990 May-Jun;53(3):20-2.

PMID:2201561
Abstract

It was shown that a phytosteroid ecdisterone which is the principle of a new tonic drug ecdisten in doses of 5-20 mg/kg is able to stimulate the primary immune reaction slightly effecting the indices of T-cell immunity activity and phagocyte functions. On increasing ecdisterone dose to 50 mg/kg inhibition of the number of antibody cells in the mouse spleen was marked.

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