Zapadniuk V I
Farmakol Toksikol. 1990 May-Jun;53(3):4-8.
The analysis of the molecular mechanisms underlying age-related changes in manifestations of pharmacokinetics, pharmacodynamics, therapeutic and toxic properties of drugs in the elderly is presented. The ways of their correction are discussed. The advances in the development of geriatric drugs (dekamevit, kvadevit, ampevit, orkomin, potassium glutaminate, rikavit, trimethylglycine) and the perspectives for the creation of new geroprotectors are described.