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In-vitro activities of tetracyclines, macrolides, fluoroquinolones and clindamycin against Mycoplasma hominis and Ureaplasma ssp. isolated in Germany over 20 years.20 多年来德国分离的人型支原体和脲原体对四环素类、大环内酯类、氟喹诺酮类和克林霉素的体外活性。
Clin Microbiol Infect. 2010 Nov;16(11):1649-55. doi: 10.1111/j.1469-0691.2009.03155.x.
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莫西沙星在婴儿肺炎支原体脑膜炎中的药代动力学。

Pharmacokinetics of moxifloxacin in an infant with Mycoplasma hominis meningitis.

机构信息

Department of Pediatrics, Duke University Medical Center, Durham, NC 27599, USA.

出版信息

Pediatr Infect Dis J. 2012 Feb;31(2):197-9. doi: 10.1097/INF.0b013e31823980c3.

DOI:10.1097/INF.0b013e31823980c3
PMID:22016080
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3358780/
Abstract

Treatment of Mycoplasma hominis meningitis in infants is limited by a lack of consensus regarding therapy and limited pharmacokinetic data for agents to which M. hominis is susceptible. We report the successful treatment of a premature infant suffering from M. hominis meningitis with doxycycline and moxifloxacin and provide a pharmacokinetic profile of moxifloxacin.

摘要

治疗人类支原体脑膜炎受到治疗方案缺乏共识和适合人类支原体感染的药物药代动力学数据有限的限制。我们报告了一例使用多西环素和莫西沙星成功治疗人类支原体脑膜炎的早产儿，并提供了莫西沙星的药代动力学特征。