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维拉帕米敏感的特发性左心室心动过速合并左侧旁路的特征及射频导管消融的疗效。

The characteristics of verapamil-sensitive idiopathic left ventricular tachycardia combined with a left accessory pathway and the effect of radiofrequency catheter ablation.

机构信息

Department of Cardiology, Cardiovascular Institute and Fuwai Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, 167 Beilishi Road, Beijing 100037, China.

出版信息

Europace. 2012 May;14(5):703-8. doi: 10.1093/europace/eur330. Epub 2011 Oct 19.

Abstract

AIMS

Verapamil-sensitive idiopathic left ventricular tachycardia (ILVT) combined with a left accessory pathway (AP) is a relatively rare condition. This study examines the characteristics of patients with this condition and the effect of radiofrequency catheter ablation (RFCA).

METHODS AND RESULTS

Catheter ablation was performed on 140 ILVT patients at a single centre from January 2004 to December 2009. A concealed left AP was found in seven patients (5%), all of whom were male, with an average age of 21 ± 9 years. Sustained ILVT and orthodromic atrioventricular reentrant tachycardia (AVRT) were induced in all seven patients. Retrograde activation through a bystander AP occurred concomitantly with ILVT, with an average tachycardia length of 346 ± 29 ms (range 310-400 ms). The location of the APs in four patients was left posterior, two of which showed a slow and decremental property, while in three it was left lateral. Ablation via a retrograde transaortic approach was performed in the seven patients. The left AP was ablated first in six patients, but ILVT was no longer induced in one and became non-sustained in another. In the seventh patient, ILVT was ablated first and this proved successful.

CONCLUSIONS

Among patients with IVLT, 5% had a concomitant left AP, most of who were young men. The location of the left AP was mainly posterior and lateral, with 30% showing a slow and decremental property. Idiopathic left ventricular tachycardia and AP should be ablated simultaneously.

摘要

目的

维拉帕米敏感型特发性左心室性心动过速(ILVT)合并左侧旁路(AP)是一种相对罕见的情况。本研究探讨了该疾病患者的特征和射频导管消融(RFCA)的效果。

方法和结果

2004 年 1 月至 2009 年 12 月,在一个单一中心对 140 例 ILVT 患者进行了导管消融。在 7 例(5%)患者中发现隐匿性左侧 AP,均为男性,平均年龄 21 ± 9 岁。7 例患者均能诱发持续性 ILVT 和顺向型房室折返性心动过速(AVRT)。ILVT 同时伴有旁路逆向激活,平均心动过速长度为 346 ± 29 ms(范围 310-400 ms)。4 例患者的 AP 位于左后,其中 2 例表现为缓慢递减特性,3 例位于左外侧。7 例患者均采用逆行经主动脉途径消融。6 例患者首先消融左侧 AP,但在 1 例患者中 ILVT 不再诱发,另 1 例患者 ILVT 转为非持续性。在第 7 例患者中,首先消融 ILVT 获得成功。

结论

在 ILVT 患者中,5%合并左侧 AP,大多数为年轻男性。左侧 AP 的位置主要在后侧和外侧,其中 30%表现为缓慢递减特性。特发性左心室性心动过速和 AP 应同时消融。

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