Department of Cardiology, General Hospital of Northern Theater Command, Shenyang, China.
Department of Cardiology, Zibo Central Hospital, Zibo, China.
Pacing Clin Electrophysiol. 2021 Apr;44(4):685-692. doi: 10.1111/pace.14192. Epub 2021 Mar 17.
The underlying mechanism of verapamil-sensitive idiopathic left ventricular tachycardia (ILVT) has been postulated to be reentrant activation in the Purkinje fiber network of the left posterior fascicle or the left anterior fascicle (LAF). However, changing of cardiac axis deviation in sinus rhythm (SR) or during ILVT after radiofrequency catheter ablation (RFCA) has been rarely analyzed.
Of the 232 patients with sustained ILVT induced and surface electrocardiogram (ECG) in SR recorded before and after RFCA, the changes of ECG morphology in SR and during ILVT were analyzed.
The surface ECG in SR changed in 114 (49.1%) patients after RFCA. ILVT could still be induced in 27 (23.7%) patients. In comparison with the original ILVT, three forms of ECG morphology were observed. In eight patients, the ILVT morphology was unchanged. In the 13 patients with ILVT axis deviation conversion after ablation, the successful target was more proximal. In the six patients with ILVT morphology change but without axis deviation conversion after ablation, the successful ablation site was more distal. Among 15 patients with recurrent ILVT during follow-up, seven patients had previous axis deviation changes in SR after RFCA, the changes maintained in four patients and recovered in three patients.
The morphology changes on surface ECG in SR after RFCA would not be a necessary prerequisite or a good endpoint for ILVT ablation. To analyze ILVT morphology changes after ablation would help to further clarify an appropriate approach for catheter ablation of ILVT.
维拉帕米敏感的特发性左心室性心动过速(ILVT)的潜在机制被认为是左后纤维束或左前纤维束(LAF)浦肯野纤维网络中的折返激活。然而,射频导管消融(RFCA)后窦性心律(SR)或 ILVT 期间心轴偏斜的变化很少被分析。
在 232 例持续性 ILVT 诱导并在 RFCA 前后记录 SR 体表心电图(ECG)的患者中,分析 SR 和 ILVT 期间 ECG 形态的变化。
RFCA 后 114 例(49.1%)患者 SR 体表 ECG 发生变化。27 例(23.7%)患者仍可诱发 ILVT。与原始 ILVT 相比,观察到三种 ECG 形态。在 8 例患者中,ILVT 形态未改变。在消融后 ILVT 轴偏转换的 13 例患者中,成功靶点更靠近近端。在消融后 ILVT 形态改变但轴偏无转换的 6 例患者中,成功消融部位更靠近远端。在 15 例随访期间复发 ILVT 的患者中,7 例患者 RFCA 后 SR 存在先前的轴偏变化,其中 4 例变化保持,3 例恢复。
RFCA 后 SR 体表 ECG 形态变化不是 ILVT 消融的必要前提或良好终点。分析消融后 ILVT 形态变化有助于进一步阐明 ILVT 导管消融的适当方法。