Department of Biology, Dalhousie University, Halifax, NS B3H 4R2, Canada.
J Exp Bot. 2012 Jan;63(2):599-616. doi: 10.1093/jxb/err310. Epub 2011 Oct 20.
Plant growth and development is largely influenced by ubiquitin-mediated regulation of protein stability. Specificity of the ubiquitination pathway is controlled mainly by the substrate-recruiting E3 ubiquitin ligases, and consequently, E3 ligases control numerous cellular processes. Recent evidence that ubiquitination plays a critical role in regulating plant responses to abiotic stresses has launched intensive efforts to identify E3 ligases that mediate plant tolerance of adverse environmental conditions. Most stress-related E3 ligases identified to date facilitate responses to environmental stimuli by modulating the abundance of key downstream stress-responsive transcription factors. In this review, the regulatory roles of ubiquitin during the plant's response to abiotic stress are summarized and highlighted.
植物的生长和发育在很大程度上受到泛素介导的蛋白质稳定性调节的影响。泛素化途径的特异性主要由底物募集的 E3 泛素连接酶控制，因此，E3 连接酶控制着许多细胞过程。最近的证据表明，泛素化在调节植物对非生物胁迫的反应中起着关键作用，这促使人们积极努力鉴定介导植物耐受不利环境条件的 E3 连接酶。迄今为止，大多数与应激相关的 E3 连接酶通过调节关键下游应激反应转录因子的丰度来促进对环境刺激的反应。在这篇综述中，总结和强调了泛素在植物应对非生物胁迫中的调节作用。
