Hays John
Deptartment of Medical Microbiology and Infectious Disease; Erasmus MC; Rotterdam, The Netherlands.
Mob Genet Elements. 2011 Jul;1(2):155-158. doi: 10.4161/mge.1.2.17632. Epub 2011 Jul 1.
Moraxella catarrhalis is a Gram-negative diplococcus that is a strict human pathogen, which for a long period of time was regarded as a simple commensal. Research now shows that this organism is a pathogen its own right and is associated with both upper and lower respiratory tract infections. Further, there appears to be a dichotomy in the pathogenic potential of M. catarrhalis with upper respiratory tract infections mainly occurring in children, and lower respiratory tract infections mainly occurring in adults with predisposing pulmonary complications e.g., chronic obstructive pulmonary disease (COPD).
卡他莫拉菌是一种革兰氏阴性双球菌，是一种严格的人类病原体，长期以来被视为一种单纯的共生菌。现在的研究表明，这种微生物本身就是一种病原体，与上、下呼吸道感染均有关联。此外，卡他莫拉菌的致病潜力似乎存在差异，上呼吸道感染主要发生在儿童中，而下呼吸道感染主要发生在有易患肺部并发症（如慢性阻塞性肺疾病（COPD））的成年人中。
