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多发性肾动脉留存的活体供肾者的结局。

Outcome of living kidney donors left with multiple renal arteries.

机构信息

Department of Surgery, Division of Transplantation, University of Minnesota, Minneapolis, MN 55414, USA.

出版信息

Clin Transplant. 2012 Jan-Feb;26(1):E7-11. doi: 10.1111/j.1399-0012.2011.01548.x. Epub 2011 Oct 23.

Abstract

Individuals with kidneys having ≥ 2 arteries appear to have an increased incidence of hypertension. Whether kidney donors in whom the remaining kidney has ≥ 2 arteries are at increased risk of hypertension is unknown. Therefore, we studied 3685 kidney donors to determine whether donors left with a kidney having ≥ 2 arteries were at increased risk of hypertension, impaired renal function, or death. Cohorts were assigned based on our practice pattern and the anatomy of the donated kidney. Of the 3685 donors, 1211 were estimated to have a remaining kidney with ≥ 2 arteries. Mean follow-up time for the single-artery group was 14.1 (± 11.0) yr and 15.3 (± 11.2) yr for the ≥ 2 artery group. Six-month hospital readmission rate was 1.4% and 1.2%, hypertension was noted in 22.4% and 21.8% and proteinuria in 9.7% and 9.6%, and estimated glomerular filtration rate at last follow-up was 62 (± 28) and 62 (± 16) for single vs. ≥ 2 renal artery groups, respectively. Our data suggest no adverse clinical sequelae nor any decrease in long-term survival for donors left with a kidney having ≥ 2 renal arteries.

摘要

有≥2 条动脉的肾脏个体似乎高血压发病率更高。尚不清楚剩余肾脏有≥2 条动脉的肾移植供者是否有更高的高血压风险。因此,我们研究了 3685 名肾移植供者,以确定剩余肾脏有≥2 条动脉的供者是否有更高的高血压、肾功能受损或死亡风险。队列是根据我们的实践模式和捐献肾脏的解剖结构分配的。在 3685 名供者中,估计有 1211 名供者的剩余肾脏有≥2 条动脉。单支动脉组的平均随访时间为 14.1(±11.0)年,≥2 支动脉组为 15.3(±11.2)年。6 个月的住院再入院率为 1.4%和 1.2%,高血压发生率分别为 22.4%和 21.8%,蛋白尿发生率分别为 9.7%和 9.6%,最后一次随访时的估计肾小球滤过率分别为 62(±28)和 62(±16)。我们的数据表明,剩余肾脏有≥2 条动脉的供者没有不良的临床后果,也没有降低长期生存率。

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