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A guide for standardizing colposcopic observations for the evaluation of topical microbicide products in the pigtailed macaque model.

作者信息

Patton Dorothy L

机构信息

Department of Obstetrics & Gynecology, University of Washington, Seattle, WA, USA.

出版信息

J Med Primatol. 2012 Feb;41(1):48-51. doi: 10.1111/j.1600-0684.2011.00516.x. Epub 2011 Oct 24.

DOI:10.1111/j.1600-0684.2011.00516.x
PMID:22017364
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4207258/
Abstract
摘要

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本文引用的文献

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Glycerol monolaurate does not alter rhesus macaque (Macaca mulatta) vaginal lactobacilli and is safe for chronic use.月桂酸单甘油酯不会改变恒河猴阴道内的乳酸杆菌，且长期使用安全。
Antimicrob Agents Chemother. 2008 Dec;52(12):4448-54. doi: 10.1128/AAC.00989-08. Epub 2008 Oct 6.
2
A summary of preclinical topical microbicide vaginal safety and chlamydial efficacy evaluations in a pigtailed macaque model.食蟹猴模型中临床前局部用杀微生物剂的阴道安全性及衣原体疗效评估总结
Sex Transm Dis. 2008 Oct;35(10):889-97. doi: 10.1097/OLQ.0b013e31817dfdb8.
3
Cervicovaginal evaluation in macaques used as a model for topical microbicide safety studies.
The Chlamydia trachomatis Plasmid and CT135 Virulence Factors Are Not Essential for Genital Tract Infection or Pathology in Female Pig-Tailed Macaques.
沙眼衣原体质粒和 CT135 毒力因子并非雌性豚尾猴生殖道感染或发病所必需。
Infect Immun. 2018 Apr 23;86(5). doi: 10.1128/IAI.00121-18. Print 2018 May.
在用作局部杀菌剂安全性研究模型的猕猴中进行宫颈阴道评估。
J Med Primatol. 2008 Feb;37 Suppl 1:65-73. doi: 10.1111/j.1600-0684.2007.00265.x.
4
Preclinical safety assessments of UC781 anti-human immunodeficiency virus topical microbicide formulations.UC781抗人类免疫缺陷病毒局部用杀微生物剂制剂的临床前安全性评估。
Antimicrob Agents Chemother. 2007 May;51(5):1608-15. doi: 10.1128/AAC.00984-06. Epub 2007 Mar 12.
5
Evaluation of -2 RANTES vaginal microbicide formulations in a nonhuman primate simian/human immunodeficiency virus (SHIV) challenge model.在非人灵长类动物猿猴/人类免疫缺陷病毒（SHIV）攻击模型中对-2趋化因子调节正常T细胞表达和分泌因子（RANTES）阴道杀微生物剂配方的评估。
AIDS Res Hum Retroviruses. 2007 Jan;23(1):33-42. doi: 10.1089/aid.2006.0076.
6
Vaginal and rectal topical microbicide development: safety and efficacy of 1.0% Savvy (C31G) in the pigtailed macaque.阴道和直肠局部用杀微生物剂的研发：1.0% Savvy（C31G）在食蟹猴中的安全性和有效性
Sex Transm Dis. 2006 Nov;33(11):691-5. doi: 10.1097/01.olq.0000216022.18321.d3.
7
Preclinical safety and efficacy assessments of dendrimer-based (SPL7013) microbicide gel formulations in a nonhuman primate model.基于树枝状大分子的（SPL7013）杀微生物剂凝胶制剂在非人灵长类动物模型中的临床前安全性和有效性评估。
Antimicrob Agents Chemother. 2006 May;50(5):1696-700. doi: 10.1128/AAC.50.5.1696-1700.2006.
8
Safety and distribution of cellulose acetate 1,2-benzenedicarboxylate (CAP), a candidate anti-HIV microbicide in rhesus macaques.醋酸纤维素邻苯二甲酸酯（CAP）作为一种抗艾滋病毒杀微生物剂候选药物在恒河猴体内的安全性及分布情况
AIDS. 2005 Oct 14;19(15):1595-9. doi: 10.1097/01.aids.0000185990.16477.47.
9
Topical estrogen protects against SIV vaginal transmission without evidence of systemic effect.局部使用雌激素可预防猴免疫缺陷病毒的阴道传播，且无全身效应的证据。
AIDS. 2004 Aug 20;18(12):1637-43. doi: 10.1097/01.aids.0000131393.76221.cc.
10
Safety and efficacy evaluations for vaginal and rectal use of BufferGel in the macaque model.猕猴模型中BufferGel经阴道和直肠使用的安全性和有效性评估。
Sex Transm Dis. 2004 May;31(5):290-6. doi: 10.1097/01.olq.0000124614.91448.d4.