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植酸酶:晶体结构、蛋白质工程及潜在生物技术应用。

Phytases: crystal structures, protein engineering and potential biotechnological applications.

机构信息

Key Laboratory of Chemical Biology and Molecular Engineering of Ministry of Education, Institute of Biotechnology, Shanxi University, Taiyuan, China.

出版信息

J Appl Microbiol. 2012 Jan;112(1):1-14. doi: 10.1111/j.1365-2672.2011.05181.x. Epub 2011 Nov 25.

DOI:10.1111/j.1365-2672.2011.05181.x
PMID:22017627
Abstract

Phytases are a group of enzymes capable of releasing phosphates from phytates, one of the major forms of phosphorus (P) in animal feeds of plant origin. These enzymes have been widely used in animal feed to improve phosphorus nutrition and to reduce phosphorus pollution in animal waste. This review covers the basic nomenclature and crystal structures of phytases and emphasizes both the protein engineering strategies used for the development of new, effective phytases with improved properties and the potential biotechnological applications of phytases.

摘要

植酸酶是一组能够从植酸中释放出磷酸的酶,植酸是植物源性动物饲料中磷(P)的主要形式之一。这些酶已广泛应用于动物饲料中,以改善磷营养,并减少动物粪便中的磷污染。本综述涵盖了植酸酶的基本命名法和晶体结构,并强调了用于开发具有改进性能的新型有效植酸酶的蛋白质工程策略,以及植酸酶的潜在生物技术应用。

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J Appl Microbiol. 2012 Jan;112(1):1-14. doi: 10.1111/j.1365-2672.2011.05181.x. Epub 2011 Nov 25.
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