Kimbrough R D
Office of the Administrator, U.S. Environmental Protection Agency, Washington, D.C. 20460.
J Toxicol Environ Health. 1990 Aug;30(4):261-71. doi: 10.1080/15287399009531428.
The tissue levels of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) measured in different species are reviewed. Based on the correlation of tissue levels and a toxic response in different species, humans are less or no more susceptible to the toxic effects of TCDD than most of the laboratory animals that have been studied. Thus, the present exposure of the general population to environmental levels of TCDD are related compounds should not be of concern.
本文综述了在不同物种中测得的2,3,7,8-四氯二苯并对二噁英(TCDD)的组织水平。基于不同物种中组织水平与毒性反应的相关性,与大多数已研究的实验动物相比,人类对TCDD的毒性作用的易感性较低或并不更高。因此,一般人群目前对环境水平的TCDD及其相关化合物的接触不应引起关注。