Cullen Eye Institute, Baylor College of Medicine, Houston, Texas 77030, USA.
J Cataract Refract Surg. 2011 Nov;37(11):2018-27. doi: 10.1016/j.jcrs.2011.05.042.
To evaluate the accuracy of refractive prediction of 4 intraocular lens (IOL) power calculation formulas in eyes with axial length (AL) greater than 25.0 mm and to propose a method of optimizing AL to improve the accuracy.
Cullen Eye Institute, Baylor College of Medicine, Houston, Texas, USA, and Department of Ophthalmology, Goethe University, Frankfurt am Main, Germany.
Case series.
Refractive prediction errors with the Holladay 1, Haigis, SRK/T, and Hoffer Q formulas were evaluated in consecutive cases. Eyes were randomized to a group used to develop the method of optimizing AL by back-calculation or a group used for validation. Further validation was performed in 2 additional data sets.
The optimized AL values were highly correlated with the IOLMaster AL (R(2) from 0.960 to 0.976). In the validating group, the method of optimizing AL significantly reduced the mean numerical errors for IOLs greater than 5.00 diopters (D) from +0.27 to +0.68 D to -0.10 to -0.02 D and for IOLs of 5.00 D or less from +1.13 to +1.87 D to -0.21 to +0.01 D, respectively (all P<.05). In 2 additional validation data sets, this method significantly reduced the percentage of eyes that would be left hyperopic.
The proposed method of optimizing AL significantly reduced the percentage of long eyes with a hyperopic outcome. Updated optimizing AL formulas by combining all eyes from the 2 study centers are proposed.
No author has a financial or proprietary interest in any material or method mentioned.
评估 4 种眼内晶状体（IOL）计算公式在眼轴（AL）大于 25.0mm 的情况下对屈光度预测的准确性，并提出一种优化 AL 的方法以提高准确性。
美国德克萨斯州休斯顿贝勒医学院 Cullen 眼科研究所和德国法兰克福歌德大学眼科。
病例系列。
连续病例评估 Holladay 1、Haigis、SRK/T 和 Hoffer Q 公式的屈光预测误差。将眼随机分为用于通过反算优化 AL 的方法的开发组或用于验证的组。在另外 2 个数据集进行了进一步验证。
优化后的 AL 值与 IOLMaster AL 高度相关（R² 从 0.960 到 0.976）。在验证组中，优化 AL 的方法显著降低了大于 5.00 屈光度（D）的 IOL 的平均数值误差，从+0.27 到+0.68D 降至-0.10 到-0.02D，对于 5.00D 或更低的 IOL，从+1.13 到+1.87D 降至-0.21 到+0.01D，差异均有统计学意义（均 P＜0.05）。在另外 2 个验证数据集，这种方法显著降低了远视眼的比例。
提出的优化 AL 方法显著降低了远视眼的比例。提出了通过结合两个研究中心的所有眼更新优化 AL 公式。
没有作者在任何材料或方法上有财务或所有权利益。
