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癫痫患者等效偶极子源定位与局灶性皮质发育不良的相关性研究。

Association between equivalent current dipole source localization and focal cortical dysplasia in epilepsy patients.

机构信息

IBCN Dr. E. de Robertis, School of Medicine, University of Buenos Aires, Paraguay 2155 (1121), Ciudad Autónoma de Buenos Aires, Argentina.

出版信息

Epilepsy Res. 2012 Feb;98(2-3):223-31. doi: 10.1016/j.eplepsyres.2011.09.018. Epub 2011 Oct 21.

DOI:10.1016/j.eplepsyres.2011.09.018
PMID:22018907
Abstract

We analysed the association between focal cortical dysplasia (FCD) visible in MRI and the location of equivalent current dipole (ECD) of single interictal scalp EEG spikes (IIS) in 11 epilepsy patients. We calculated several indicators of distance of ECDs to the FCD border. The results confirm some previous studies suggesting that the epileptogenic zone associated to the location of ECDs extends beyond the FCD visible in MRI. The analysis suggests the ECDs to be in a shell parallel to part of the FCD surface.

摘要

我们分析了 11 例癫痫患者的 MRI 可见局灶性皮质发育不良(FCD)与单个发作间期头皮 EEG 棘波(IIS)的等效电流偶极子(ECD)位置之间的关系。我们计算了 ECD 到 FCD 边界的几个距离指标。结果证实了一些先前的研究,表明与 ECD 位置相关的致痫区超出了 MRI 可见的 FCD。分析表明 ECD 位于与 FCD 表面部分平行的壳内。

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