Developmental Therapeutics Program, University of Colorado Cancer Center, Aurora, CO 80045, USA.
Crit Rev Oncol Hematol. 2012 Jul;83(1):1-10. doi: 10.1016/j.critrevonc.2011.09.008. Epub 2011 Oct 21.
In the last 15 years there has been a major shift in the laws governing medical use of cannabis in the United States. Corresponding with this change there has been escalating interest in the role that cannabis, commonly referred to as marijuana, and cannabinoids play in the care of patients with cancer. This review will examine cannabis' and cannabinoids' current and potential roles in cancer care. Specifically, we will examine five areas of cannabis medicine: (1) pharmacologic properties of cannabis; (2) its potential role in the development of human cancers, particularly smoking-related malignancies; (3) cannabinoids' potential as anti-cancer therapies; (4) cannabis and cannabinoids in the palliation of common cancer-associated symptoms; (5) current legal status of cannabis for medical purposes in the United States.
在过去的 15 年中，美国管理医疗用途大麻的法律发生了重大转变。随着这一变化，人们对大麻（通常称为大麻）和大麻素在癌症患者护理中的作用越来越感兴趣。本综述将探讨大麻和大麻素在癌症护理中的当前和潜在作用。具体来说，我们将研究大麻医学的五个领域：（1）大麻的药理特性；（2）它在人类癌症发展中的潜在作用，特别是与吸烟有关的恶性肿瘤；（3）大麻素作为抗癌疗法的潜力；（4）大麻和大麻素在缓解常见癌症相关症状中的作用；（5）目前美国大麻用于医疗目的的法律地位。
