Department of Physical Medicine and Rehabilitation, Eastern Virginia Medical School, Norfolk, Virginia 23507-1927, USA.
Am J Phys Med Rehabil. 2011 Dec;90(12):1064-7. doi: 10.1097/PHM.0b013e31823285c7.
Children with cerebral palsy and other neurologic diseases often present with sialorrhea. Intraglandular botulinum neurotoxin is being increasingly reported to be clinically effective for the treatment of sialorrhea. This treatment is becoming more popular in recent years because of being less invasive than surgical procedures. In addition, fewer adverse effects have been documented compared with oral or topical anticholinergic medication. We report the first case in a child with cerebral palsy who developed serious acute sialadenitis with submandibular sialolithiasis after intraglandular botulinum neurotoxin injection for sialorrhea.
患有脑瘫和其他神经疾病的儿童常伴有流涎。腺体注射肉毒神经毒素治疗流涎的临床效果越来越受到关注。与手术相比，这种治疗方法具有创伤小的优势，近年来越来越受欢迎。此外，与口服或局部使用抗胆碱能药物相比，其不良反应的报道也较少。我们报告了首例脑瘫患儿在接受腺体注射肉毒神经毒素治疗流涎后出现严重的急性唾液腺炎伴下颌下涎石症的病例。
