University Eye Clinic, University of Bern, Switzerland.
Biol Psychol. 2012 Jan;89(1):191-4. doi: 10.1016/j.biopsycho.2011.10.007. Epub 2011 Oct 19.
To make an antisaccade away from a stimulus, one must also suppress the more reflexive prosaccade to the stimulus. Whether this inhibition is diffuse or specific for saccade direction is not known. We used a paradigm examining inter-trial carry-over effects. Twelve subjects performed sequences of four identical antisaccades followed by sequences of four prosaccades randomly directed at the location of the antisaccade stimulus, the location of the antisaccade goal, or neutral locations. We found two types of persistent antisaccade-related inhibition. First, prosaccades in any direction were delayed only in the first trial after the antisaccades. Second, prosaccades to the location of the antisaccade stimulus were delayed more than all other prosaccades, and this persisted from the first to the fourth subsequent trial. These findings are consistent with both a transient global inhibition and a more sustained focal inhibition specific for the location of the antisaccade stimulus.
为了进行反扫视，还必须抑制对刺激物的更反射性的扫视。这种抑制是弥散性的还是专门针对扫视方向的尚不清楚。我们使用了一种检查试验间延续效应的范式。12 名受试者按顺序进行了四组相同的反扫视，然后是四组随机指向反扫视刺激物位置、反扫视目标位置或中性位置的扫视。我们发现了两种持续的反扫视相关抑制。首先，任何方向的扫视在反扫视后的第一次试验中都被延迟。其次，与反扫视刺激物位置的扫视比其他所有扫视都要延迟更多，而且这种情况从第一次持续到第四次后续试验。这些发现与暂时的全局抑制和更持续的专门针对反扫视刺激物位置的焦点抑制都一致。
