Caceres E, Zaharia M, Calderon R
Instituto Nacional de Enfermedades Neoplásicas, Lima, Peru.
Semin Surg Oncol. 1990;6(4):231-3. doi: 10.1002/ssu.2980060408.
Records of 182 consecutive patients with the diagnosis of operable osteogenic sarcoma, treated between 1954 through 1980 by the Breast, Bone and Mixed Tumors Department of the Instituto Nacional de Enfermedades Neoplasicas (Lima, Peru), were reviewed to study the incidence of regional lymph node metastases in this disease. All the patients included in this study had radical surgery, which means the complete resection of the bone where the tumor is located, including the proximal joint, which permitted excision of the regional lymph nodes. Nineteen patients (10.4%) had evidence of sarcoma metastatic to draining lymph nodes. A comprehensive analysis of the literature shows that the incidence of metastasis to the lymph nodes in this study, is higher than those cited in a review of the literature, probably due to the policy in the management of osteogenic sarcoma in our institution, during the period of study.
回顾了1954年至1980年间，秘鲁利马国家肿瘤研究所乳腺、骨与混合性肿瘤科收治的182例经诊断为可手术的骨肉瘤患者的记录，以研究该疾病区域淋巴结转移的发生率。本研究纳入的所有患者均接受了根治性手术，即完整切除肿瘤所在的骨骼，包括近端关节，以便切除区域淋巴结。19例患者（10.4%）有肉瘤转移至引流淋巴结的证据。对文献的综合分析表明，本研究中淋巴结转移的发生率高于文献综述中引用的发生率，这可能是由于在研究期间，我们机构对骨肉瘤的治疗策略所致。
