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骨肉瘤的不典型胸部CT表现:16例病例回顾

Unusual thoracic CT manifestations of osteosarcoma: review of 16 cases.

作者信息

Rastogi Ruchi, Garg Rachana, Thulkar Sanjay, Bakhshi Sameer, Gupta Ajay

机构信息

Department of Radiology, All India Institute of Medical Sciences, New Delhi, India 110029.

出版信息

Pediatr Radiol. 2008 May;38(5):551-8. doi: 10.1007/s00247-007-0735-3. Epub 2008 Feb 2.

DOI:10.1007/s00247-007-0735-3
PMID:18246342
Abstract

Pulmonary metastases are common in osteosarcoma and the most common appearance is of multiple well-defined nodules in the lung parenchyma. However, a variety of atypical locations and presentations of osteosarcoma metastasis can occur in the thorax. We present a review of the thoracic CT findings in 16 patients with histopathologically confirmed osteosarcoma with unusual thoracic manifestations. The 16 patients were selected out of a total 136 patients who received a chest CT scan for osteosarcoma during a period of 3 years in a tertiary care hospital. Unusual imaging findings included a solitary large ossified lung mass, ossified mediastinal and hilar lymph nodes, an esophagomediastinal fistula, lymphangitic carcinomatosis, pulmonary artery tumor emboli, a solitary large pleural deposit along the major fissure, multiple pleural deposits, diffuse pleural calcification, pneumothorax, diaphragmatic deposits, an isolated chest wall deposit without lung involvement, and primary osteosarcoma of the rib. Our findings of lymphangitic carcinomatosis in a living patient as well as calcified mediastinal lymphadenopathy leading to esophageal fistula are unique in the literature, and there are only a few case reports of our other findings.

摘要

肺转移在骨肉瘤中很常见,最常见的表现是肺实质内多个边界清晰的结节。然而,骨肉瘤转移在胸部可出现各种非典型的部位和表现。我们对16例经组织病理学证实的骨肉瘤且有不寻常胸部表现的患者的胸部CT结果进行了综述。这16例患者是从一家三级医院在3年期间因骨肉瘤接受胸部CT扫描的136例患者中挑选出来的。不寻常的影像学表现包括孤立的大的骨化性肺肿块、骨化的纵隔和肺门淋巴结、食管纵隔瘘、淋巴管癌病、肺动脉肿瘤栓子、沿叶间裂的孤立的大的胸膜沉积物、多个胸膜沉积物、弥漫性胸膜钙化、气胸、膈肌沉积物、无肺部受累的孤立胸壁沉积物以及肋骨原发性骨肉瘤。我们在一名在世患者中发现淋巴管癌病以及钙化的纵隔淋巴结病导致食管瘘,这在文献中是独特的,我们的其他发现仅有少数病例报告。

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本文引用的文献

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Bone metastases in osteosarcoma patients treated with neoadjuvant or adjuvant chemotherapy: the Rizzoli experience in 52 patients.接受新辅助或辅助化疗的骨肉瘤患者的骨转移:里佐利对52例患者的经验。
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CT features of osteosarcoma lung metastasis: a retrospective study of 127 patients.CT 特征在骨肉瘤肺转移中的表现:127 例患者的回顾性研究。
J Bras Pneumol. 2023 Apr 28;49(2):e20220433. doi: 10.36416/1806-3756/e20220433. eCollection 2023.
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Pulmonary metastasis of osteosarcoma: multiple presentations in a single patient.骨肉瘤的肺转移:同一患者的多种表现
J Bras Pneumol. 2022 Apr 20;48(2):e20210478. doi: 10.36416/1806-3756/e20210478.
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Osteogenic Sarcoma Presenting with Skip, Lymph Nodal, Pulmonary, Pleural Metastases and Malignant Effusion: An Unusual Appearance on Bone Scan.骨肉瘤伴跳跃性、淋巴结、肺、胸膜转移及恶性胸腔积液:骨扫描的不寻常表现
Indian J Nucl Med. 2021 Jan-Mar;36(1):78-79. doi: 10.4103/ijnm.IJNM_177_20. Epub 2021 Mar 4.
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Case Report: Primary Extraskeletal Osteosarcoma in the Lung and Pulmonary Artery.病例报告:肺及肺动脉原发性骨外骨肉瘤
Front Oncol. 2021 Apr 22;11:673494. doi: 10.3389/fonc.2021.673494. eCollection 2021.
Can Assoc Radiol J. 2005 Oct;56(4):214-8.
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[Recurrent spontaneous pneumothorax complicating osteosarcoma pulmonary metastasis].[复发性自发性气胸并发骨肉瘤肺转移]
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Imaging findings of extrapulmonary metastases of osteosarcoma.骨肉瘤肺外转移的影像学表现。
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