National Hospital Organization, Osaka-Minami Medical Center, Osaka, Japan.
Spine (Phila Pa 1976). 2012 Mar 1;37(5):E315-7. doi: 10.1097/BRS.0b013e318239ccbd.
Review article.
To discuss indications and timing of surgery for patients with significant ossification of the posterior longitudinal ligament (OPLL) who show no or only mild myelopathic symptoms.
Among patients with cervical spinal cord injury, the incidence of patients with OPLL is relatively high, and most had no obvious symptoms of cervical myelopathy.
These topics were discussed on the basis of clinical practice guidelines for ossification of the posterior longitudinal ligament as published in 2005 by the Japanese Orthopaedic Association and the Committee on Research into OPLL under the auspices of the Ministry of Health, Labor and Welfare.
No evidence supports the usefulness of surgery for patients with significant OPLL without or with only mild cervical myelopathy.
"Prophylactic" surgery for patients with significant OPLL without or with only mild cervical myelopathy cannot be recommended on the basis of the existing evidence.
研究设计：综述文章
目的：讨论无明显或仅有轻度脊髓病症状的严重后纵韧带骨化症（OPLL）患者的手术适应证和时机。
摘要背景数据：在颈椎脊髓损伤患者中，OPLL 的发病率相对较高，大多数患者无明显的颈椎脊髓病症状。
方法：这些主题是基于日本骨科协会 2005 年发布的后纵韧带骨化症临床实践指南以及厚生劳动省 OPLL 研究委员会讨论得出的。
结果：没有证据支持对无明显或仅有轻度颈脊髓病的严重 OPLL 患者进行手术的有效性。
结论：根据现有证据，不能推荐对无明显或仅有轻度颈脊髓病的严重 OPLL 患者进行“预防性”手术。
