Navino C, Barbè M C, Chiarinotti D, Guida G E, Cusaro C, Fortina A, De Leo M, Pecora S, Verzetti G
Ospedale Maggiore, Novara Divisione di Nefrologia e Dialisi.
Minerva Urol Nefrol. 1990 Jan-Mar;42(1):13-6.
A kinetic evaluation of dialytic methods using a diffusive-convective mechanism in comparison to the standard bicarbonate dialysis was performed in order to verify the possible therapeutic uses. The "kinetic" comparison of PFD and HDF to HBD, using equal quantities of dialysate, showed no significant change in the mention of uremic toxins of small molecular weight and a more efficient capacity to extract beta 2M by the diffusive-convective methods. The biophysical evaluation of dialysis still appears to represent the best means of defining the clearance possibilities and of identifying the most suitable technique for achieving a dialytic adequacy.
为了验证可能的治疗用途，对使用扩散对流机制的透析方法与标准碳酸氢盐透析进行了动力学评估。在使用等量透析液的情况下，将PFD和HDF与HBD进行“动力学”比较，结果显示小分子尿毒症毒素的提及量没有显著变化，并且通过扩散对流方法提取β2M的能力更高。透析的生物物理评估似乎仍然是确定清除可能性和识别实现透析充分性最合适技术的最佳方法。
