Ghezzi P M, Gervasio R
Ospedale S. Croce, Cuneo, Divisione di Nefrologia e Dialisi.
Minerva Urol Nefrol. 1990 Jan-Mar;42(1):27-9.
The risks of back-filtration that occur with the use of high hydraulic permeability membranes with haemodialytic techniques in the course of which the difference between forced and necessary ultrafiltration is compensated for by correcting transmembrane pressure in favour of the dialyser compartment. In this way a form of concealed haemodiafiltration is attained in which the replacement fluid is the dialysing solution, annulling, owing to the possible consequences of the transit of bacterial endotoxins into the circulation, all the advantages linked to the use of these membranes. It is concluded by suggesting the implementation of well controlled haemodiafiltration through the careful quali-quantitative evaluation of the replacement fluid.
在血液透析技术中使用高水力渗透性膜时会出现反向过滤风险,在此过程中,通过调整跨膜压力以利于透析器腔室来补偿强制超滤和必要超滤之间的差异。通过这种方式实现了一种隐蔽的血液透析滤过形式,其中置换液为透析液,由于细菌内毒素进入循环可能产生的后果,抵消了使用这些膜所带来的所有优势。文章最后建议通过对置换液进行仔细的定性定量评估来实施严格控制的血液透析滤过。