Repacholi Michael H, Lerchl Alexander, Röösli Martin, Sienkiewicz Zenon, Auvinen Anssi, Breckenkamp Jürgen, d'Inzeo Guglielmo, Elliott Paul, Frei Patrizia, Heinrich Sabine, Lagroye Isabelle, Lahkola Anna, McCormick David L, Thomas Silke, Vecchia Paolo
Department of Information Engineering, Electronics and Telecommunications, "La Sapienza" University of Rome, Italy.
Bioelectromagnetics. 2012 Apr;33(3):187-206. doi: 10.1002/bem.20716. Epub 2011 Oct 21.
We conducted a systematic review of scientific studies to evaluate whether the use of wireless phones is linked to an increased incidence of the brain cancer glioma or other tumors of the head (meningioma, acoustic neuroma, and parotid gland), originating in the areas of the head that most absorb radiofrequency (RF) energy from wireless phones. Epidemiology and in vivo studies were evaluated according to an agreed protocol; quality criteria were used to evaluate the studies for narrative synthesis but not for meta-analyses or pooling of results. The epidemiology study results were heterogeneous, with sparse data on long-term use (≥ 10 years). Meta-analyses of the epidemiology studies showed no statistically significant increase in risk (defined as P < 0.05) for adult brain cancer or other head tumors from wireless phone use. Analyses of the in vivo oncogenicity, tumor promotion, and genotoxicity studies also showed no statistically significant relationship between exposure to RF fields and genotoxic damage to brain cells, or the incidence of brain cancers or other tumors of the head. Assessment of the review results using the Hill criteria did not support a causal relationship between wireless phone use and the incidence of adult cancers in the areas of the head that most absorb RF energy from the use of wireless phones. There are insufficient data to make any determinations about longer-term use (≥ 10 years).
我们对科学研究进行了系统综述，以评估使用无线电话是否与脑癌胶质瘤或其他头部肿瘤（脑膜瘤、听神经瘤和腮腺肿瘤）的发病率增加有关，这些肿瘤起源于头部最能吸收无线电话射频（RF）能量的区域。根据商定的方案对流行病学和体内研究进行了评估；使用质量标准对研究进行评估以进行叙述性综合，但不用于荟萃分析或结果合并。流行病学研究结果参差不齐，长期使用（≥10年）的数据稀少。流行病学研究的荟萃分析表明，使用无线电话导致成人大脑癌症或其他头部肿瘤的风险没有统计学上的显著增加（定义为P<0.05）。对体内致癌性、肿瘤促进和遗传毒性研究的分析也表明，暴露于射频场与脑细胞的遗传毒性损伤、脑癌或其他头部肿瘤的发病率之间没有统计学上的显著关系。使用希尔标准对综述结果进行评估不支持使用无线电话与在头部最能吸收无线电话使用产生的射频能量的区域发生成人癌症之间存在因果关系。没有足够的数据来对长期使用（≥10年）做出任何判断。
