Department of Otorhinolaryngology, The University of Texas Health Science Center at Houston School of Medicine, Houston, Texas, USA.
Head Neck. 2012 Oct;34(10):1492-6. doi: 10.1002/hed.21926. Epub 2011 Oct 22.
Sinonasal hemangiopericytomas are rare low-grade sarcomas. The role of endoscopic management has not been adequately studied.
This study was conducted through retrospective medical chart review of patients seen with sinonasal hemangiopericytomas at 2 institutions over a 19-year period. Demographic, clinicopathological, and surgical information was analyzed with descriptive statistics.
Thirteen patients with a diagnosis of sinonasal hemangiopericytomas were treated. The most common symptoms were obstruction (69%) and epistaxis (35%). All tumors were localized in the nasal cavity, and half had extension to 1 or more sinuses. Resection was performed endoscopically in 6 patients. Median intraoperative blood loss was 500 mL; median operative time was 165 minutes. Two patients received postoperative radiation. There were no recurrences with a median follow-up of 25 months. Three patients presented with recurrences, 2 local and 1 distant, up to 13 years after primary tumor removal.
Surgery for sinonasal hemangiopericytomas can be challenging; both endoscopic and open approaches may be used to treat these highly vascular tumors.
鼻腔鼻窦血管外皮细胞瘤是一种罕见的低度恶性肉瘤。内镜治疗的作用尚未得到充分研究。
本研究通过对 2 家机构在 19 年期间就诊的鼻腔鼻窦血管外皮细胞瘤患者的回顾性病历进行回顾性研究。采用描述性统计方法分析人口统计学、临床病理学和手术信息。
13 例诊断为鼻腔鼻窦血管外皮细胞瘤的患者接受了治疗。最常见的症状是阻塞(69%)和鼻出血(35%)。所有肿瘤均局限于鼻腔,一半以上侵犯 1 个或多个鼻窦。6 例患者行内镜下切除术。术中中位出血量为 500ml;中位手术时间为 165 分钟。2 例患者术后接受放疗。中位随访 25 个月无复发。3 例患者在原发性肿瘤切除后 13 年内复发,2 例局部复发,1 例远处转移。
鼻腔鼻窦血管外皮细胞瘤的手术治疗具有挑战性;内镜和开放手术均可用于治疗这些高度血管化的肿瘤。