Florek R C, Triffon D W, Mann D E, Ringel S P, Reiter M J
Department of Medicine, University of Colorado Health Sciences Center, Denver 80262.
West J Med. 1990 Jul;153(1):24-7.
In examining the incidence and progression of electrocardiographic abnormalities in 45 patients with myotonic dystrophy, 26 (58%) of whom at entry had at least 1 electrocardiographic abnormality, we found conduction abnormalities in 17 (38%). In 21 patients (47%), new abnormalities developed during follow-up (mean, 4.6 years). The overall incidence of electrocardiographic abnormalities increased to 78%, and the incidence of conduction defects increased to 62%. Second-degree or complete atrioventricular block did not develop in any of the patients. Pseudoinfarction patterns were common at entry and during follow-up and were not correlated with evidence of clinical coronary artery disease. There was no correlation between the presence of electrocardiographic abnormalities and apparent disease severity.
在对45例强直性肌营养不良患者的心电图异常发生率及进展情况进行检查时，其中26例（58%）在入组时至少有1项心电图异常，我们发现17例（38%）存在传导异常。在21例患者（47%）中，随访期间（平均4.6年）出现了新的异常。心电图异常的总体发生率增至78%，传导缺陷的发生率增至62%。所有患者均未发生二度或完全性房室传导阻滞。假性梗死图形在入组时和随访期间均很常见，且与临床冠状动脉疾病证据无关。心电图异常的存在与明显的疾病严重程度之间无相关性。
