Delektorskiĭ V V, Romanenko V N, Gupalo L A, Balakishieva F I
Vestn Dermatol Venerol. 1990(4):32-6.
Twenty rabbits were infected with Treponema pallidum suspension. Ten animals were injected with solusulfone, the rest with cefamezin. Specific features of syphilis induced by a pool of Treponemas are described, such as T. pallidum ultrastructure, formation of a specific granule, form of the agent aggression. Solusulfone treatment was associated with activation of phagocytosis, that manifested by a shift of the incomplete/complete phagocytosis ratio towards the reaction completion; however, intact T. pallidum were detectable even in 72 hrs after the drug injection. Cefamezin had no effect on the cysts and cyst-like formations at the beginning of the treatment course but these forms of the agent were already undetectable in 48 hours.
二十只兔子感染了梅毒螺旋体悬液。十只动物注射了磺胺苯砜，其余的注射了头孢米诺。描述了由一组梅毒螺旋体引起的梅毒的具体特征，如梅毒螺旋体的超微结构、特异性颗粒的形成、病原体侵袭的形式。磺胺苯砜治疗与吞噬作用的激活有关，表现为不完全/完全吞噬作用比率向反应完成方向的转变；然而，即使在注射药物72小时后仍可检测到完整的梅毒螺旋体。在治疗过程开始时，头孢米诺对囊肿和囊肿样结构没有影响，但在48小时内这些病原体形式已无法检测到。
