Poulsen A, Kobayasi T, Secher L, Weismann K
Acta Derm Venereol. 1985;65(5):367-73.
The ultrastructure of treponema pallidum obtained directly from human chancres by biopsy was studied by electron microscopy. The treponemes were enveloped by a trilaminar cytoplasmic membrane and a trilaminar periplastic membrane. The central part of the periplastic membrane corresponds to the protective mucoid layer. In undamaged organisms bunches of axial filaments were seen to entwine the whole cytoplasmic body without any disruption or overlapping. The number of axial filaments varied between three and four. Identical nose pieces were demonstrable in both ends of the treponemes. Axial filaments and nose pieces seem to differ from those of Nichols' strain.
通过活检直接从人体梅毒溃疡中获取梅毒螺旋体，用电镜对其超微结构进行了研究。梅毒螺旋体被一层三层的细胞质膜和一层三层的周质膜所包裹。周质膜的中央部分相当于保护性黏液层。在未受损的菌体中，可以看到一束束轴丝缠绕着整个细胞质体，没有任何断裂或重叠。轴丝的数量在三根到四根之间变化。在梅毒螺旋体的两端都可以证实有相同的鼻状结构。轴丝和鼻状结构似乎与Nichols株的不同。
