Department of Internal Medicine, Chonnam National University Hospital, Gwangju, Korea.
J Korean Med Sci. 2011 Oct;26(10):1391-3. doi: 10.3346/jkms.2011.26.10.1391. Epub 2011 Oct 1.
Pulmonary alveolar microlithiasis (PAM) is a rare disease with unknown etiology and pathogenesis. It is characterized by diffuse, innumerable, and minute calculi, called microlithiasis in the alveoli. More than half of reported cases are asymptomatic at the time of diagnosis. We describe the first case of PAM in Korea. A 19-yr-old man without respiratory symptoms presented with interstitial thickening on the chest radiograph. His chest high resolution CT scan showed diffusely scattered, ill defined tiny micronodules and interstitial thickening. Open lung biopsy confirmed the diagnosis of PAM. He was followed up for 6 months without treatment, and no progression was noticed.
肺肺泡微结石症（PAM）是一种病因和发病机制不明的罕见疾病。其特征是弥漫性、无数的微小结石，称为肺泡微结石症。超过一半的报道病例在诊断时无症状。我们描述了首例韩国 PAM 病例。一名 19 岁男性无呼吸道症状，胸部 X 线片显示间质增厚。其胸部高分辨率 CT 扫描显示弥漫性散在、边界不清的微小微结节和间质增厚。开胸肺活检证实了 PAM 的诊断。他未经治疗随访了 6 个月，未发现病情进展。
