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无痛性皮肤供区:关于 Opsite、猩红热毒素和布比卡因的对照双盲试验

Painless split skin donor sites: a controlled double-blind trial of Opsite, scarlet red and bupivacaine.

作者信息

Morris W T, Lamb A M

机构信息

Department of Surgery, Auckland Hospital, New Zealand.

出版信息

Aust N Z J Surg. 1990 Aug;60(8):617-20. doi: 10.1111/j.1445-2197.1990.tb07442.x.

DOI:10.1111/j.1445-2197.1990.tb07442.x
PMID:2202283
Abstract

A prospective randomized double-blind trial comparing Opsite alone, Opsite after application of bupivacaine, scarlet ointment dressing alone and scarlet ointment after bupivacaine was done to assess the effect of these four dressing regimens on split skin donor site pain and healing. Significantly less pain was reported by those dressed with Opsite and this was thought to be due to the immobility of an Opsite dressing. Many of the patients dressed with scarlet ointment felt no pain. It was concluded that movement of dressings is the main factor in pain production and that bupivacaine appeared to have no effect. There was no difference in healing rates between those treated with Opsite and those treated with scarlet ointment. It is concluded that using Opsite is a convenient way of preventing donor site pain, but that to gain maximum advantage from this it should not be applied under tension.

摘要

开展了一项前瞻性随机双盲试验,比较单独使用Opsite敷料、布比卡因应用后使用Opsite敷料、单独使用红油膏敷料以及布比卡因应用后使用红油膏敷料这四种敷料方案对中厚皮片供皮区疼痛和愈合的影响。使用Opsite敷料的患者报告的疼痛明显较少,这被认为是由于Opsite敷料固定不动所致。许多使用红油膏敷料的患者没有感到疼痛。得出的结论是,敷料的移动是产生疼痛的主要因素,而布比卡因似乎没有效果。使用Opsite敷料的患者和使用红油膏敷料的患者的愈合率没有差异。得出的结论是,使用Opsite敷料是预防供皮区疼痛的一种便捷方法,但要想充分发挥其优势,不应在张力下应用。

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