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在出生前开始的随机对照试验,以预防幼儿龋齿,在 6-7 岁时进行重新评估。

Reassessment at 6-7 years of age of a randomized controlled trial initiated before birth to prevent early childhood caries.

机构信息

Australian Research Centre for Population Oral Health, School of Dentistry, The University of Adelaide, Adelaide, South Australia, Australia.

出版信息

Community Dent Oral Epidemiol. 2012 Apr;40(2):116-24. doi: 10.1111/j.1600-0528.2011.00643.x. Epub 2011 Oct 24.

DOI:10.1111/j.1600-0528.2011.00643.x
PMID:22022927
Abstract

OBJECTIVES

To assess whether the effect of providing mothers with guidance during pregnancy and when the child was 6 and 12 months old, which had drastically reduced the prevalence of early childhood caries at 20 months of age, would be sustained at 6-7 years of age.

METHODS

Children, whose mothers had been enrolled in a randomized controlled trial during pregnancy and a comparison group of similar school children, were examined for the presence of caries by the South Australian School Dental Services (SA SDS) at 6-7 years of age.

RESULTS

Of 625 eligible trial participants, 277 (44%) participated in the follow-up and dental records were available for 187 of them (30%). Loss to follow-up and reasons for it were similar in the intervention and control groups. At 6-7 years of age, 33% of children in the trial had caries compared with 42% in the SA SDS comparison group (n = 263). All measures of caries severity (d(3)mft, d(3)mfs and SiC(30)) were lower, but not significantly so, in the intervention than in the control group. Children in the comparison group of school children had more severe caries than those in the trial (P < 0.01) and in the intervention group especially (P < 0.005). Children in both randomized groups suffered significantly less toothache than those in the comparison group (P < 0.001).

CONCLUSIONS

Providing new mothers with guidance on caries prevention helps to reduce early childhood caries and has a sustainable effect up to school age.

摘要

目的

评估在妊娠期间以及儿童 6 个月和 12 个月时为母亲提供指导,是否会降低幼儿龋齿的患病率,这种效果是否会持续到 6-7 岁。

方法

对参加过妊娠期间随机对照试验的儿童及其类似的学校儿童对照组进行检查,由南澳大利亚学校牙科服务(SA SDS)在 6-7 岁时检查龋齿的发生情况。

结果

在 625 名符合条件的试验参与者中,有 277 名(44%)参加了随访,其中 187 名(30%)有牙齿记录。干预组和对照组的失访率和原因相似。在 6-7 岁时,试验组中有 33%的儿童患有龋齿,而 SA SDS 对照组中有 42%的儿童患有龋齿(n=263)。所有龋齿严重程度的测量指标(dmft、dmfs 和 SiC30)在干预组中均低于对照组,但无统计学意义。与试验组相比,学校儿童对照组的儿童龋齿更为严重(P < 0.01),尤其是干预组(P < 0.005)。两组随机分组的儿童的牙痛明显少于对照组(P < 0.001)。

结论

为新妈妈提供龋齿预防指导有助于降低幼儿龋齿的患病率,这种效果可持续到学龄期。

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