Department of Pathobiological Sciences, School of Veterinary Medicine, University of Wisconsin, 2015 Linden Drive, Madison, WI 53706-1102, USA.
Vet Clin North Am Food Anim Pract. 2011 Nov;27(3):631-6, vii-viii. doi: 10.1016/j.cvfa.2011.07.009.
Both ante mortem and post mortem contamination of foods of animal origin commonly occurs. Food manufacturing practices fail to reliably kill Mycobacterium avium subsp. paratuberculosis (MAP) due to its innate resistance to heat and other physical factors. While medical science does not agree on the human health consequences of MAP exposure, this potentially zoonotic pathogen is found in a significant proportion of people with a disease bearing marked similarity to Johne’s disease (ie, Crohn’s disease). Control of MAP infections in farm animals to mitigate the risk of human exposure is one additional reason for on-farm measures to control Johne’s disease.
生前和死后污染动物源食品的情况都很常见。由于其对热和其他物理因素的固有抵抗力,食品制造实践未能可靠地杀死禽分枝杆菌亚种。虽然医学科学对 MAP 暴露对人类健康的影响意见不一,但这种潜在的人畜共患病病原体在很大一部分患有与约翰病(即克罗恩病)具有明显相似性的患者中都有发现。控制农场动物中的 MAP 感染以降低人类暴露的风险是农场控制约翰病措施的另一个原因。