Dubernet Catherine
Université Paris-Sud, Chatenay-Malabry, France.
Bull Cancer. 2011 Nov;98(11):1363-71. doi: 10.1684/bdc.2011.1468.
The concept of drug targeting has resulted in a considerable variety of tools within nanotechnology, whose potentials in the special field of cancer are very interesting. There is a strong link between the structure and the surface of the vector on the one hand, and the biological target thus accessible on the other hand, as illustrated a number of typical examples. Parallel developments were made in the fields of therapy and diagnosis, stage by stage. The challenges now live in the combination of approaches widely reported under the terminology of "theranostics".
药物靶向的概念在纳米技术领域催生了各种各样的工具，这些工具在癌症这一特殊领域的潜力非常令人关注。一方面，载体的结构与表面之间存在着紧密联系，另一方面，由此可实现与生物靶点的对接，一些典型例子说明了这一点。治疗和诊断领域也在逐步取得并行发展。目前的挑战在于如何将在“治疗诊断学”术语下广泛报道的各种方法结合起来。
