Division of Plastic Surgery, European Institute of Oncology, Via Ripamonti 435, 20141 Milan, Italy.
Nat Rev Clin Oncol. 2011 Oct 25;8(12):742-7. doi: 10.1038/nrclinonc.2011.159.
Nipple-sparing mastectomy (NSM) is a surgical protocol designed to reduce the disabling psychological effects of radical or skin-sparing mastectomy. The preservation of the nipple-areola complex produces a more-natural result of the breast reconstruction, but this preservation is suspected of increasing tumor local recurrence. To reduce this risk, different approaches have been proposed: restrict the inclusion criteria and/or add localized radiation therapy. The local recurrence rate in recent series of patients receiving NSM is comparable with the local recurrence rate in modified radical or skin-sparing mastectomies. Today, the quality of the subcutaneous mastectomy technique allows for a more radical glandular removal, especially in the retroareolar area; therefore, local recurrence is observed in 3-6% of patients at 5 years, consistent with traditional mastectomy.
保留乳头乳晕复合体的乳房切除术(NSM)是一种旨在降低根治性或保留皮肤乳房切除术导致的致残性心理影响的手术方案。乳房重建的结果更自然,但这种保留被怀疑会增加肿瘤局部复发的风险。为了降低这种风险,已经提出了不同的方法:限制纳入标准和/或添加局部放射治疗。在接受 NSM 的患者的最新系列中,局部复发率与改良根治性或保留皮肤乳房切除术的局部复发率相当。如今,皮下乳房切除术技术的质量允许更彻底的腺体切除,特别是在乳晕后区域;因此,5 年内 3-6%的患者出现局部复发,与传统乳房切除术一致。