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本文引用的文献

1
Use of potentially inappropriate medicines in elderly: A prospective study in medicine out-patient department of a tertiary care teaching hospital.老年人潜在不适当用药的使用:一项在三级教学医院内科门诊的前瞻性研究。
Indian J Pharmacol. 2010 Apr;42(2):95-8. doi: 10.4103/0253-7613.64499.
2
Inappropriate prescribing and adverse drug events in older people.老年人不适当用药及药物不良事件
BMC Geriatr. 2009 Jan 28;9:5. doi: 10.1186/1471-2318-9-5.
3
Appropriate prescribing in elderly people: how well can it be measured and optimised?老年人的合理用药:其测量与优化效果如何?
Lancet. 2007 Jul 14;370(9582):173-184. doi: 10.1016/S0140-6736(07)61091-5.
4
Prevalence of inappropriate medication using Beers criteria in Japanese long-term care facilities.日本长期护理机构中使用Beers标准评估的不适当用药情况。
BMC Geriatr. 2006 Jan 11;6:1. doi: 10.1186/1471-2318-6-1.
5
Inappropriate drug prescribing in older adults: the updated 2002 Beers criteria--a population-based cohort study.老年人不适当用药:2002年更新的《Beers标准》——一项基于人群的队列研究
Br J Clin Pharmacol. 2005 Aug;60(2):137-44. doi: 10.1111/j.1365-2125.2005.02391.x.
6
Polypharmacy and inappropriate medication use in Singapore nursing homes.新加坡养老院中的多重用药及不适当用药情况。
Ann Acad Med Singap. 2004 Jan;33(1):49-52.
7
Updating the Beers criteria for potentially inappropriate medication use in older adults: results of a US consensus panel of experts.更新老年人潜在不适当用药的Beers标准:美国专家共识小组的结果。
Arch Intern Med. 2003;163(22):2716-24. doi: 10.1001/archinte.163.22.2716.
8
Assessing medication appropriateness in the elderly: a review of available measures.评估老年人用药的合理性:现有措施综述
Drugs Aging. 2000 Jun;16(6):437-50. doi: 10.2165/00002512-200016060-00004.
9
Longitudinal trends in prescribing for elderly patients: two surveys four years apart.老年患者处方的纵向趋势:相隔四年的两项调查。
Br J Gen Pract. 1994 Dec;44(389):571-5.

使用Beers标准和Phadke标准评估老年患者处方的适宜性及其比较。

Evaluation of the appropriateness of prescribing in geriatric patients using Beers criteria and Phadke's criteria and comparison thereof.

作者信息

Shah Rima B, Gajjar Bharat M, Desai Sagun V

机构信息

Department of Pharmacology, SBKS Medical Institute and Research Center, Piparia, Vadodara, India.

出版信息

J Pharmacol Pharmacother. 2011 Oct;2(4):248-52. doi: 10.4103/0976-500X.85948.

DOI:10.4103/0976-500X.85948
PMID:22025852
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3198519/
Abstract

OBJECTIVES

To evaluate appropriateness of prescribing medicines in geriatric patients using both Beers criteria and Phadke's criteria and compare them for validation of Phadke's criteria as a tool to evaluate rationality of prescribing in elderly.

MATERIALS AND METHODS

A cross-sectional prospective observational study was conducted and the baseline data were collected from different inpatient and outpatient departments in Shree Krishna Hospital (SKH), Karamsad. A total of 400 patients of geriatric age group (≥65 years) from various inpatient and outpatient departments of SKH were included in the study. Relevant information from patients included in the study was recorded in a structured proforma from their case files. Data were evaluated for appropriateness of prescribing by using both Beers criteria and Phadke's criteria and comparison between the two criteria was also carried out.

RESULTS

Out of total 400 patients, 291 (72.75%) patients were prescribed appropriately according to Beers criteria. Based on Phadke's criteria, 158 (39.5%) prescriptions were rational, 129 (32.3%) were semirational and 113 (28.3%) were irrational. Mean rationality score on a 30-point semiscientific scale was found to be 18.47 ± 9.66 (mean ± SD). The comparison of outcome by both the criteria showed no significant difference in appropriateness of prescribing (P>0.05).

CONCLUSIONS

Inappropriate prescribing is common in elderly patients. Beers criteria is a well-established method for evaluating appropriateness of prescribing. This study has shown that Phadke's method of evaluating rationality of prescriptions compares equally well and hence can be a valuable objective tool for assessing appropriateness of prescribing in geriatric patients.

摘要

目的

使用Beers标准和Phadke标准评估老年患者用药的合理性,并对两者进行比较,以验证Phadke标准作为评估老年人合理用药工具的有效性。

材料与方法

进行了一项横断面前瞻性观察研究,从卡拉姆萨德市施里·克里希纳医院(SKH)的不同住院部和门诊部收集基线数据。该研究纳入了SKH各住院部和门诊部共400名老年年龄组(≥65岁)的患者。研究中纳入患者的相关信息从其病历中记录在结构化表格中。通过使用Beers标准和Phadke标准评估数据的用药合理性,并对这两个标准进行比较。

结果

在总共400名患者中,根据Beers标准,291名(72.75%)患者用药合理。根据Phadke标准,158张(39.5%)处方合理,129张(32.3%)半合理,113张(28.3%)不合理。在30分的半科学量表上,平均合理性得分为18.47±9.66(均值±标准差)。两个标准的结果比较显示,用药合理性无显著差异(P>0.05)。

结论

老年患者用药不当情况常见。Beers标准是评估用药合理性的成熟方法。本研究表明,Phadke评估处方合理性的方法效果相当,因此可以成为评估老年患者用药合理性的有价值的客观工具。