Park Se Young, Jin Seon Pil, Yeom Bora, Kim Shin Woo, Cho So Yun, Lee Jong Hee
Department of Dermatology, Seoul National University Boramae Hospital, Seoul, Korea.
Ann Dermatol. 2011 Sep;23 Suppl 1(Suppl 1):S45-7. doi: 10.5021/ad.2011.23.S1.S45. Epub 2011 Sep 30.
Fibroma of the tendon sheath is an uncommon soft tissue tumor presenting as a solitary, slow-growing, firm, painless, small nodule, which shows strong attachment to the tendon or tendon sheath. It is usually localized on fingers and hand tendons in adults between the age of 20 and 40 years old. This case concerns a 61-year-old man presenting with a 5-year history of multiple cutaneous nodules on both palms and soles. Skin biopsy confirmed fibroma of the tendon sheath. Blood tests showed a high titer of rheumatoid factor and positivity to anti-nuclear antibody. No case of fibroma of the tendon sheath occurring multifocally on both palms and soles has been previously reported. Herein, we report on a very rare case of multiple fibromas of the tendon sheath arising from palms and soles, which supports the pathogenetic hypothesis that this tumor may be a reactive process rather than a true neoplasm.
腱鞘纤维瘤是一种罕见的软组织肿瘤，表现为单个、生长缓慢、质地坚硬、无痛的小结节，与肌腱或腱鞘紧密相连。它通常发生于20至40岁成年人的手指和手部肌腱。本病例为一名61岁男性，双掌和双足底有多个皮肤结节，病史5年。皮肤活检确诊为腱鞘纤维瘤。血液检查显示类风湿因子高滴度及抗核抗体阳性。此前未见腱鞘纤维瘤在双掌和双足底多发的病例报道。在此，我们报告一例极为罕见的起源于双掌和双足底的多发腱鞘纤维瘤病例，这支持了该肿瘤可能是一种反应性过程而非真正肿瘤的发病机制假说。
