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腱鞘纤维瘤:细针穿刺细胞学检查中的诊断难题。

Fibroma of the tendon sheath: A diagnostic dilemma on fine-needle aspiration cytology.

作者信息

Nasit Jitendra G, Dhruva Gauravi

机构信息

Department of Pathology, Government Medical College, SSG Hospital, Vadodara, Gujarat, India.

Department of Pathology, Pandit Deendayal Upadhyay Government Medical College and Hospital, Rajkot, Gujarat, India.

出版信息

J Cytol. 2015 Jul-Sep;32(3):207-9. doi: 10.4103/0970-9371.168906.

DOI:10.4103/0970-9371.168906
PMID:26729987
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4687217/
Abstract

Fibroma of the tendon sheath (FTS) is an uncommon benign soft tissue tumor (STS) of the tendon sheath. Clinical and radiological features are not distinctive enough to clinch the diagnosis preoperatively. Although histological features are well described, diagnostic cytological features of FTS are still lacking. Till date only two reports describe the fine-needle aspiration cytology (FNAC) findings of FTS. The present case is a 50-year-old female who presented with a slow growing nodule on the right thigh over a period of 2 years. FNAC revealed low cell yield with loose clusters of fibrotic spindle cells and stellate cells intermingled with fibro-collagenous and myxoid matrix. Few cells showed mild degree of nuclear atypia. Necrosis and atypical mitoses were not seen. Cytology findings were suggestive of benign/low-grade fibroblastic or fibromyxoid lesion. Histology confirmed the diagnosis of FTS. This article discusses the diagnostic role of FNAC in FTS with its differential diagnosis.

摘要

腱鞘纤维瘤(FTS)是一种罕见的腱鞘良性软组织肿瘤(STS)。临床和放射学特征不足以在术前确诊。虽然组织学特征已有详尽描述,但FTS的诊断性细胞学特征仍不明确。迄今为止,仅有两篇报告描述了FTS的细针穿刺抽吸细胞学检查(FNAC)结果。本病例为一名50岁女性,其右大腿出现一个缓慢生长的结节,病程长达2年。FNAC显示细胞产量低,有散在的纤维化梭形细胞和星状细胞团,与纤维胶原和黏液样基质混合。少数细胞显示轻度核异型性。未见坏死和非典型有丝分裂。细胞学检查结果提示为良性/低级别成纤维细胞或纤维黏液样病变。组织学检查确诊为FTS。本文讨论了FNAC在FTS诊断中的作用及其鉴别诊断。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9797/4687217/f67d1dfdda36/JCytol-32-207-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9797/4687217/4ed5babd0978/JCytol-32-207-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9797/4687217/f67d1dfdda36/JCytol-32-207-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9797/4687217/4ed5babd0978/JCytol-32-207-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9797/4687217/f67d1dfdda36/JCytol-32-207-g002.jpg

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本文引用的文献

1
Fibroma of the tendon sheath - a rare hand tumor.腱鞘纤维瘤——一种罕见的手部肿瘤。
Pol Przegl Chir. 2012 Dec;84(12):651-6. doi: 10.2478/v10035-012-0107-z.
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Multiple fibromas of tendon sheath: unusual presentation.腱鞘多发性纤维瘤:不寻常的表现。
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