Kwon Hyok Bu, Choi Yun Seok, Lee Joon Ho, Jin Sang Yun, Kim Beom Joon, Lee Seung Ho, Lee Ai Young
Department of Dermatology, Dongguk University Ilsan Hospital, College of Medicine, Dongguk University, Goyang, Korea.
Ann Dermatol. 2011 Sep;23 Suppl 1(Suppl 1):S68-71. doi: 10.5021/ad.2011.23.S1.S68. Epub 2011 Sep 30.
Verrucous carcinoma is an unusual, non-metastasizing, distinct variant of squamous cell carcinoma composed of four subtypes according to the site of occurrence: oral type, anogenital type, plantar type, and other cutaneous sites. Oral type verrucous carcinoma usually shows slow progression with a low incidence of metastases. Treatment of verrcous carcinoma is challenging; multiple medical and surgical therapies are often attempted, with limited success. We reported on 2 cases of verrucous carcinoma of the lip treated with topical imiquimod and debulking therapy.
疣状癌是一种不常见的、非转移性的、独特的鳞状细胞癌变体,根据发生部位可分为四种亚型:口腔型、肛门生殖器型、足底型和其他皮肤部位型。口腔型疣状癌通常进展缓慢,转移发生率低。疣状癌的治疗具有挑战性;常常尝试多种药物和手术治疗方法,但成功率有限。我们报告了2例采用局部咪喹莫特和减积疗法治疗的唇部疣状癌病例。