Centre for Disease Control & Prevention, Ministry of Health and Medical, Education, Tehran, Iran.
Malar J. 2011 Oct 27;10:319. doi: 10.1186/1475-2875-10-319.
Malaria continues to be a global public health challenge, particularly in developing countries. Delivery of prompt and effective diagnosis and treatment of malaria cases, detection of malaria epidemics within one week of onset and control them in less than a month, regular disease monitoring and operational classification of malaria are among the major responsibilities of the national malaria programme. The study was conducted to determine these indicators at the different level of primary health care facilities in malaria-affected provinces of Iran
In this survey, data was collected from 223 health facilities including health centres, malaria posts, health houses and hospitals as well as the profile of all 5, 836 recorded malaria cases in these facilities during the year preceding the survey. Descriptive statistics (i.e. frequencies, percentages) were used to summarize the results and Chi square test was used to analyse data.
All but one percent of uncomplicated cases took appropriate and correctly-dosed of anti-malarial drugs in accordance to the national treatment guideline. A larger proportion of patients [85.8%; 95% CI: 84.8 - 86.8] were also given complete treatment including anti-relapse course, in line with national guidelines. About one third [35.0%; 95% CI: 33.6 - 36.4] of uncomplicated malaria cases were treated more than 48 hours after first symptoms onset. Correspondingly, half of severe malaria cases took recommended anti-malarial drugs for severe or complicated disease more than 48 hours of onset of first symptoms. The latter cases had given regular anti-malarial drugs promptly.The majority of malaria epidemics [97%; 95% CI: 90.6 - 100] in study areas were detected within one week of onset, but only half of epidemics were controlled within four weeks of detection. Just half of target districts had at least one health facility/emergency site with adequate supply and equipment stocks. Nevertheless, only one-third of them [33% (95% CI: 0.00 - 67.8)] had updated inventory of malaria foci on quarterly basis.
To sum up, malaria case management still constitutes a public health problem in Iran. Additionally, data suggest scarcity in management and evaluation of malaria foci, detection and control of malaria epidemics as well as assignment of emergency sites across different regions of the country. Consequently, massive and substantial investments need to be made at the Ministry of Health to coordinate national malaria control programmes towards achieving determined goals and targets.
疟疾仍然是全球公共卫生面临的一个挑战,尤其是在发展中国家。及时有效地诊断和治疗疟疾病例,在发病一周内发现疟疾疫情并在一个月内控制疫情,定期进行疾病监测以及对疟疾进行操作性分类,这些都是国家疟疾规划的主要职责。本研究旨在确定伊朗疟疾流行省份不同级别基层卫生保健机构的这些指标。
在这项调查中,从包括卫生中心、疟疾站、卫生所和医院在内的 223 个卫生机构以及这些机构在调查前一年记录的所有 5836 例疟疾病例的档案中收集了数据。使用描述性统计(即频率、百分比)来总结结果,并使用卡方检验进行数据分析。
除 1%的病例外,所有未合并症病例均按照国家治疗指南,使用适当且剂量正确的抗疟药物进行治疗。按照国家指南,更大比例的患者[85.8%;95%CI:84.8-86.8]接受了包括抗复发疗程在内的完整治疗。大约三分之一[35.0%;95%CI:33.6-36.4]的未合并症疟疾病例在首次症状出现后 48 小时以上才开始治疗。相应地,一半的重症疟疾病例在首次症状出现后 48 小时以上才开始使用推荐的抗疟药物治疗严重或复杂疾病。这些病例及时给予了常规抗疟药物。研究地区[97%;95%CI:90.6-100]的大部分疟疾疫情都在发病后一周内得到了检测,但只有一半的疫情在发现后四周内得到了控制。只有一半的目标地区至少有一个卫生机构/紧急场所,其供应和设备库存充足。然而,只有三分之一的地区[33%(95%CI:0.00-67.8)]每季度更新疟疾病灶的库存。
综上所述,在伊朗,疟疾病例管理仍然是一个公共卫生问题。此外,数据表明,在疟疾病灶的管理和评估、疟疾疫情的检测和控制以及全国各地紧急场所的分配方面存在不足。因此,卫生部需要进行大规模实质性投资,以协调国家疟疾控制规划,实现既定目标。