Restrepo-Alape Leonardo D, Toro-Zapata Hernán D, Muñoz-Loaiza Aníbal
Departamento de Matemáticas, Facultad de Ciencias Básicas y Tecnologías, Universidad del Quindío, Armenia, Colombia.
Rev Salud Publica (Bogota). 2010 Dec;12(6):1033-41. doi: 10.1590/s0124-00642010000600015.
Dengue fever is a common vector-borne disease in tropical and subtropical areas. It is transmitted to humans by the bite of an infected female Aedes mosquito. Since no vaccines are currently available which can protect against infection, disease control relies on controlling the mosquito population. This work was aimed at modelling such mosquito's population dynamics regarding chemical control of the adult population and its acquired resistance to chemicals. The model was analysed by using classical dynamic system theory techniques and mosquito growth threshold was determined as this establishes when a particular population may prosper in the environment or when it is likely to disappear. A suitable chemical control strategy was developed from such threshold. Simulations were made in control and non-control scenarios; this determined the degree of control application effectiveness against different levels of acquired resistance.
登革热是热带和亚热带地区常见的媒介传播疾病。它通过受感染的雌性伊蚊叮咬传播给人类。由于目前没有可预防感染的疫苗,疾病控制依赖于控制蚊子数量。这项工作旨在对这种蚊子的种群动态进行建模,涉及成蚊的化学控制及其对化学物质的获得性抗性。使用经典动态系统理论技术对模型进行分析,并确定蚊子生长阈值,因为这决定了特定种群在环境中何时可能繁荣或何时可能消失。从该阈值制定了合适的化学控制策略。在有控制和无控制的情况下进行了模拟;这确定了针对不同水平的获得性抗性的控制应用效果程度。