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代谢综合征的营养干预:系统评价。

Nutritional interventions in metabolic syndrome: a systematic review.

机构信息

Escola Nacional de Saúde Pública, FIOCRUZ, Universidade Federal do Estado do Rio de Janeiro, Rio de Janeiro, RJ, Brasil.

出版信息

Arq Bras Cardiol. 2011 Sep;97(3):260-5. doi: 10.1590/s0066-782x2011001200012.

DOI:10.1590/s0066-782x2011001200012
PMID:22030698
Abstract

There is no consensus on the most appropriate nutritional strategy for treating metabolic syndrome (MS), such that cardiovascular risk is reduced. This study was designed to assess the strength of evidence of the benefits of various nutritional interventions in MS remission. Performed in Medline, Cochrane Library and PubMed databases, the virtual search consisted of randomized clinical trials published between 1999 and 2009 in any language, studies involving individuals aged 18 or older and diagnosed with MS, regardless of the criterion. The Boolean operator and was used in the combination of the MeSH terms "Metabolic Syndrome", "Metabolic x Syndrome" and "Metabolic Syndrome X", the entry terms "Dysmetabolic Syndrome X", Metabolic Cardiovascular Syndrome," "Metabolic X Syndrome" and "Syndrome X, Metabolic", plus the terms "diet", "intervention and diet", "treatment and diet" and "supplementation". For each study included in the review, we estimated the prevalence of MS and the calculation of effectiveness after the follow-up period. Relative risk measures for each study were described by Forest Plot. We identified 131 articles, which, after eligibility criteria, resulted in 15 studies. These studies were divided into four groups: normocaloric diet associated with exercise; isolated normocaloric diet, low-calorie diet combined with exercises; and isolated low-calorie diet. Tests with low-calorie diet associated with exercising revealed higher efficiency values, helping to emphasize the global aspects of lifestyle change in the treatment of MS, in which healthy and low-calorie diet should be complemented with the practice of physical activity.

摘要

目前对于代谢综合征(MS)的治疗,尚无统一的最佳营养策略,以降低心血管风险。本研究旨在评估各种营养干预措施在 MS 缓解中的益处的证据强度。在 Medline、Cochrane 图书馆和 PubMed 数据库中进行了虚拟检索,检索时间为 1999 年至 2009 年期间发表的任何语言的随机临床试验,研究对象为年龄在 18 岁或以上且被诊断为 MS 的个体,无论采用何种标准。布尔运算符“and”用于组合 MeSH 术语“代谢综合征”、“代谢 x 综合征”和“代谢综合征 X”、入口术语“代谢综合征 X”、“代谢心血管综合征”、“代谢 X 综合征”和“代谢综合征 X”,以及术语“饮食”、“干预和饮食”、“治疗和饮食”和“补充”。对于纳入审查的每项研究,我们估计了 MS 的患病率,并在随访期后计算了有效性。每个研究的相对风险测量均通过森林图描述。我们共识别出 131 篇文章,经资格标准筛选后,纳入了 15 项研究。这些研究分为四组:与运动相结合的正常热量饮食;单纯正常热量饮食、低热量饮食与运动相结合;以及单纯低热量饮食。与运动相结合的低热量饮食试验显示出更高的效率值,这有助于强调生活方式改变的整体方面在 MS 的治疗中,健康和低热量的饮食应辅以体育锻炼。

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