Ucak Alper, Ugur Murat, Onan Burak, Arslan Gökhan, Alp Ibrahim, Ulusoy Eralp, Yilmaz Ahmet Turan
Department of Cardiovascular Surgery, GATA Haydarpasa Education Hospital, Istanbul, Turkey.
Acta Cardiol. 2011 Oct;66(5):627-34. doi: 10.1080/ac.66.5.2131089.
This study aims to assess the effects of bileaflet preservation versus conventional technique during mitral valve replacement (MVR) on left ventricular functions and end-systolic stress (ESS).
Between September 2005 and January 2009, sixty-five patients with mitral regurgitation underwent MVR surgery. In a non-randomized fashion, 34 patients had conventional MVR without chordal/leaflet preservation (group I, c-MVR), and 31 had MVR with total chordal/bileaflet preservation (group II, b-MVR). A prospective clinical and echocardiographic follow-up of patients was performed preoperatively, at 3 months and by 1 year postoperatively.
Left ventricular end-systolic/end-diastolic dimensions and volumes decreased by 1 year in the b-MVR group. Left ventricular ESS decreased only in the bileaflet sparing MVR group after surgery, and this decrease was significant by 1 year, compared with the c-MVR group (P = 0.008). Left atrial diameter significantly decreased in both groups. Only one patient died, due to posterior wall rupture after a c-MVR procedure. One patient undergoing a b-MVR procedure needed re-operation because of prosthetic valve endocarditis.
Bileaflet preservation during MVR has a beneficial effect on left ventricular function, compared with conventional MVR. Left ventricular ESS improves after bileaflet-sparing MVR and may be an important indicator of myocardial function after mitral valve surgery.
本研究旨在评估二尖瓣置换术(MVR)期间双叶瓣保留与传统技术相比对左心室功能和收缩末期应力(ESS)的影响。
2005年9月至2009年1月期间,65例二尖瓣反流患者接受了MVR手术。以非随机方式,34例患者接受了不保留腱索/瓣叶的传统MVR(I组,c-MVR),31例接受了保留全部腱索/双叶瓣的MVR(II组,b-MVR)。对患者进行术前、术后3个月和术后1年的前瞻性临床和超声心动图随访。
b-MVR组左心室收缩末期/舒张末期内径和容积在1年后减小。术后仅双叶瓣保留的MVR组左心室ESS降低,与c-MVR组相比,1年后这种降低具有显著性(P = 0.008)。两组左心房直径均显著减小。仅1例患者死亡,死于c-MVR手术后的后壁破裂。1例接受b-MVR手术的患者因人工瓣膜心内膜炎需要再次手术。
与传统MVR相比,MVR期间双叶瓣保留对左心室功能有有益影响。双叶瓣保留的MVR术后左心室ESS改善,可能是二尖瓣手术后心肌功能的重要指标。