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传统二尖瓣置换术与完全保留腱索二尖瓣置换术:对左心室功能和收缩末期应力的影响。

Conventional versus complete chordal-sparing mitral valve replacement: effects on left ventricular function and end-systolic stress.

作者信息

Ucak Alper, Ugur Murat, Onan Burak, Arslan Gökhan, Alp Ibrahim, Ulusoy Eralp, Yilmaz Ahmet Turan

机构信息

Department of Cardiovascular Surgery, GATA Haydarpasa Education Hospital, Istanbul, Turkey.

出版信息

Acta Cardiol. 2011 Oct;66(5):627-34. doi: 10.1080/ac.66.5.2131089.

Abstract

BACKGROUND

This study aims to assess the effects of bileaflet preservation versus conventional technique during mitral valve replacement (MVR) on left ventricular functions and end-systolic stress (ESS).

METHODS

Between September 2005 and January 2009, sixty-five patients with mitral regurgitation underwent MVR surgery. In a non-randomized fashion, 34 patients had conventional MVR without chordal/leaflet preservation (group I, c-MVR), and 31 had MVR with total chordal/bileaflet preservation (group II, b-MVR). A prospective clinical and echocardiographic follow-up of patients was performed preoperatively, at 3 months and by 1 year postoperatively.

RESULTS

Left ventricular end-systolic/end-diastolic dimensions and volumes decreased by 1 year in the b-MVR group. Left ventricular ESS decreased only in the bileaflet sparing MVR group after surgery, and this decrease was significant by 1 year, compared with the c-MVR group (P = 0.008). Left atrial diameter significantly decreased in both groups. Only one patient died, due to posterior wall rupture after a c-MVR procedure. One patient undergoing a b-MVR procedure needed re-operation because of prosthetic valve endocarditis.

CONCLUSION

Bileaflet preservation during MVR has a beneficial effect on left ventricular function, compared with conventional MVR. Left ventricular ESS improves after bileaflet-sparing MVR and may be an important indicator of myocardial function after mitral valve surgery.

摘要

背景

本研究旨在评估二尖瓣置换术(MVR)期间双叶瓣保留与传统技术相比对左心室功能和收缩末期应力(ESS)的影响。

方法

2005年9月至2009年1月期间,65例二尖瓣反流患者接受了MVR手术。以非随机方式,34例患者接受了不保留腱索/瓣叶的传统MVR(I组,c-MVR),31例接受了保留全部腱索/双叶瓣的MVR(II组,b-MVR)。对患者进行术前、术后3个月和术后1年的前瞻性临床和超声心动图随访。

结果

b-MVR组左心室收缩末期/舒张末期内径和容积在1年后减小。术后仅双叶瓣保留的MVR组左心室ESS降低,与c-MVR组相比,1年后这种降低具有显著性(P = 0.008)。两组左心房直径均显著减小。仅1例患者死亡,死于c-MVR手术后的后壁破裂。1例接受b-MVR手术的患者因人工瓣膜心内膜炎需要再次手术。

结论

与传统MVR相比,MVR期间双叶瓣保留对左心室功能有有益影响。双叶瓣保留的MVR术后左心室ESS改善,可能是二尖瓣手术后心肌功能的重要指标。

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