Department of Radiodiagnosis, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
Neuroimaging Clin N Am. 2011 Nov;21(4):859-66, viii. doi: 10.1016/j.nic.2011.07.006. Epub 2011 Sep 3.
Fungal infections of the central nervous system range from chronic indolent forms to acute fulminant forms causing significant morbidity and mortality. They often show atypical and variable neuroradiologic findings because of the absence of typical inflammatory response. The neuroradiologist must have high degree of suspicion in immunocompromised patients regarding the possibility of central nervous system fungal infections and keep in mind the appearances of various fungi even when immune response is intact. Next is to identify the pattern of involvement whether hematogenous or direct sinonasal and then make a well-informed speculation regarding the type of the pathogen based on the clinical features and imaging appearance.
中枢神经系统真菌感染的范围从慢性惰性形式到急性暴发性形式，导致发病率和死亡率显著增加。由于缺乏典型的炎症反应，它们通常表现出非典型和可变的神经放射学表现。神经放射科医生必须对免疫功能低下的患者保持高度怀疑，警惕中枢神经系统真菌感染的可能性，并牢记各种真菌的表现，即使免疫反应完整时也是如此。接下来要确定受累模式是血源性还是直接经鼻窦，并根据临床特征和影像学表现，对病原体的类型进行明智的推测。
