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[重症监护烧伤病房的病原体谱及感染途径]

[Pathogen spectrum and pathways of infection at an intensive care burn unit].

作者信息

Kistler D, Jahns N, Pichulla K, Hettich R

机构信息

Klinik für Verbrennungs- und Plastische Wiederherstellungschirurgie, Klinikum der RWTH Aachen.

出版信息

Anasth Intensivther Notfallmed. 1990 Jun;25(3):216-21.

PMID:2203274
Abstract

Coagulase-negative staphylococci have gained increasing importance in burns, whereas interest is no longer focussed on Pseudomonas bacteria. By means of microbiological analysis of swabs taken from patients, environment and staff, we trailed the routes of infection in an intensive-care unit for burns. Analysis of patients: In 27 out of 11 patients the same biotype of Staphylococcus epidermidis could be identified; 22 of these occurred in swabs from wounds. The phagotypification of Staphylococcus aureus showed the same phagotype in 28 out of 41 swabs taken from infected wounds of 10 patients. The pathogen mostly caused the destruction of already healed grafts in a later phase of the treatment. Further microbiological analysis showed a severe infestation of the patients by enterococci. Analysis of environment: Here, greatly increased counts of coagulase-negative staphylococci of the same lysotype as in the patients could be demonstrated. Analysis of staff: The naso-pharyngeal area is of minor importance in the spreading of germs, whereas that of protective clothing and especially the hands should be considered to be more crucial. Regular environmental tests enable rapid detection of hygienic errors so that appropriate countermeasures can be taken.

摘要

凝固酶阴性葡萄球菌在烧伤治疗中变得越来越重要,而人们对假单胞菌的关注不再那么集中。通过对取自患者、环境和工作人员的拭子进行微生物分析,我们追踪了烧伤重症监护病房的感染途径。患者分析:在111名患者中的27名患者身上,可鉴定出相同生物型的表皮葡萄球菌;其中22例出现在伤口拭子中。对金黄色葡萄球菌进行噬菌体型鉴定显示,从10名患者受感染伤口采集的41份拭子中,有28份具有相同的噬菌体型。该病原体在治疗后期大多导致已愈合的移植皮片遭到破坏。进一步的微生物分析显示患者受到肠球菌的严重感染。环境分析:在环境中,可以证明与患者身上相同溶菌型的凝固酶阴性葡萄球菌数量大幅增加。工作人员分析:鼻咽部位在病菌传播中不太重要,而防护服尤其是手部的病菌传播应被视为更为关键。定期进行环境检测能够快速发现卫生失误,以便采取适当的应对措施。

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