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中国一犬源 H5N2 流感病毒的遗传特征分析。

Genetic characterization of a novel influenza A virus H5N2 isolated from a dog in China.

机构信息

Shandong Provincial Key Laboratory of Animal Biotechnology and Disease Control and Prevention, Taian, Shandong 271018, China.

出版信息

Vet Microbiol. 2012 Mar 23;155(2-4):409-16. doi: 10.1016/j.vetmic.2011.08.017. Epub 2011 Aug 22.

Abstract

An influenza virus, A/canine/Shandong/JT01/2009, has been isolated from a dog exhibiting classical flu signs in China. HAI and NAI assays subtyped A/canine/Shandong/JT01/2009 as a H5N2 like virus. Phylogenetic reconstructions indicated strong relationships with viruses from various hosts and dispersed geographic locations. These analyses indicate A/canine/Shandong/JT01/2009 is a novel virus generated by complex reassortment of the viral segments.

摘要

一株流感病毒,A/犬/山东/JT01/2009,已从中国一只表现出典型流感症状的犬中分离得到。血凝抑制 (HAI) 和神经氨酸酶抑制 (NAI) 试验将 A/犬/山东/JT01/2009 鉴定为 H5N2 样病毒。系统进化重建表明,该病毒与来自不同宿主和分散地理位置的病毒具有很强的关系。这些分析表明,A/犬/山东/JT01/2009 是一种新型病毒,是由病毒片段的复杂重配产生的。

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