Szaluś-Jordanow Olga, Golke Anna, Dzieciątkowski Tomasz, Czopowicz Michał, Kardas Michał, Mickiewicz Marcin, Moroz-Fik Agata, Łobaczewski Andrzej, Markowska-Daniel Iwona, Frymus Tadeusz
Department of Small Animal Diseases with Clinic, Institute of Veterinary Medicine, Warsaw University of Life Sciences-SGGW, Nowoursynowska 159c, 02-776 Warsaw, Poland.
Department of Preclinical Sciences, Institute of Veterinary Medicine, Warsaw University of Life Sciences (SGGW), Ciszewskiego 8, 02-786 Warsaw, Poland.
Microorganisms. 2024 Mar 29;12(4):689. doi: 10.3390/microorganisms12040689.
In summer 2023, during an outbreak of highly pathogenic avian influenza (HPAI) in cats in Poland, a 16-year-old dog was presented to the veterinary clinic with persistent, debilitating, dry cough, submandibular lymphadenomegaly, mild serous nasal discharge, and left apical heart murmur. A preliminary diagnosis of kennel cough was made and the treatment with amoxicillin/clavulanic acid and dexamethasone was initiated. Due to the lack of improvement within 2 days, a blood check-up, thoracic radiography and ultrasonography, and echocardiography were performed. Moreover, a rapid test for orthomyxovirus type A antigen in a throat swab was carried out and proved positive. The result was verified using RT-qPCR, which yielded a positive result for A/H5N1 influenza virus and negative results for A/H1N1, A/H3N2, type B influenza, and SARS-CoV-2. This case indicates that HPAI should be considered as a differential diagnosis not only in cats, but also in dogs with upper respiratory tract disease, particularly in regions experiencing A/H5N1 avian influenza outbreaks.
2023年夏季，波兰发生猫高致病性禽流感（HPAI）疫情期间，一只16岁的犬只因持续、衰弱性干咳、颌下淋巴结肿大、轻度浆液性鼻分泌物和左心尖部心脏杂音被送至兽医诊所。初步诊断为犬窝咳，并开始使用阿莫西林/克拉维酸和地塞米松进行治疗。由于2天内病情未见改善，遂进行了血液检查、胸部X光和超声检查以及超声心动图检查。此外，还对咽喉拭子进行了甲型正粘病毒抗原快速检测，结果呈阳性。使用逆转录定量聚合酶链反应（RT-qPCR）对结果进行了验证，结果显示H5N1流感病毒呈阳性，H1N1、H3N2、乙型流感病毒和严重急性呼吸综合征冠状病毒2（SARS-CoV-2）呈阴性。该病例表明，对于上呼吸道疾病的犬只，尤其是在经历H5N1禽流感疫情的地区，不仅在猫中，而且在犬中都应将HPAI视为鉴别诊断。
