Whitehouse P J
Professor of Neurology, Psychiatry, Neuroscience Psychology, Nursing, Bioethics, Organizational Behavior, University AlzheimerCenter, Cleveland, Ohio, USA.
Dialogues Clin Neurosci. 2000 Jun;2(2):162-7. doi: 10.31887/DCNS.2000.2.2/pwhitehouse.
The growing number of individuals affected by dementia will intensify the ethical issues that emerge in clinical practice and research, issues early in disease relate to genetic testing, use of medications in mildly affected persons, and diagnostic disclosure. Research issues relate to appropriate informed consent processes, conflict of interests, and research design issues, such as the use of placebos and the use of biological tissues, in the later stages of disease concern about appropriate therapeutic goals and end-of-life care is appropriate.
受痴呆症影响的人数不断增加，这将加剧临床实践和研究中出现的伦理问题。疾病早期的问题涉及基因检测、轻度患者用药以及诊断信息披露。研究问题涉及适当的知情同意程序、利益冲突以及研究设计问题，如安慰剂的使用和生物组织的使用。在疾病后期，关于适当的治疗目标和临终关怀的问题也很重要。
