Carmichael T R, Gelfand Y, Welsh N H
Department of Ophthalmology, University of the Witwatersrand, Johannesburg, Republic of South Africa.
Br J Ophthalmol. 1990 Sep;74(9):528-31. doi: 10.1136/bjo.74.9.528.
During an 18-month period a prospective randomised trial was conducted on 40 selected patients with bacterial corneal ulcers. Two groups were compared: one was treated with antibiotic only and the other with antibiotic plus steroid. Complications were similar in the two groups. No delay in healing rate of the ulcers was seen with the use of topical steroid. Two methods of assessing visual improvement are discussed, but it was not possible to demonstrate a difference in visual outcome between the two groups.
在18个月的时间里,对40例选定的细菌性角膜溃疡患者进行了一项前瞻性随机试验。比较了两组:一组仅用抗生素治疗,另一组用抗生素加类固醇治疗。两组的并发症相似。使用局部类固醇并未观察到溃疡愈合速度延迟。讨论了两种评估视力改善的方法,但无法证明两组在视力结果上存在差异。