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局部用类固醇药物治疗中央及旁中央角膜溃疡

Topical steroids in the treatment of central and paracentral corneal ulcers.

作者信息

Carmichael T R, Gelfand Y, Welsh N H

机构信息

Department of Ophthalmology, University of the Witwatersrand, Johannesburg, Republic of South Africa.

出版信息

Br J Ophthalmol. 1990 Sep;74(9):528-31. doi: 10.1136/bjo.74.9.528.

DOI:10.1136/bjo.74.9.528
PMID:2203467
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1042200/
Abstract

During an 18-month period a prospective randomised trial was conducted on 40 selected patients with bacterial corneal ulcers. Two groups were compared: one was treated with antibiotic only and the other with antibiotic plus steroid. Complications were similar in the two groups. No delay in healing rate of the ulcers was seen with the use of topical steroid. Two methods of assessing visual improvement are discussed, but it was not possible to demonstrate a difference in visual outcome between the two groups.

摘要

在18个月的时间里,对40例选定的细菌性角膜溃疡患者进行了一项前瞻性随机试验。比较了两组:一组仅用抗生素治疗,另一组用抗生素加类固醇治疗。两组的并发症相似。使用局部类固醇并未观察到溃疡愈合速度延迟。讨论了两种评估视力改善的方法,但无法证明两组在视力结果上存在差异。

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本文引用的文献

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The effect of cortisone on experimental pseudomonas corneal ulcers.可的松对实验性铜绿假单胞菌角膜溃疡的作用
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The management of ocular herpes.眼部疱疹的管理
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