HLA-A*33:25是通过序列分型鉴定出的一个新等位基因，在韩国人群中是一个有充分文献记载的等位基因。
HLA-A*33:25, a novel allele identified by sequence-based typing, is a well-documented allele in Koreans.
作者信息
Joo S Y, Song E Y, Huh J Y, Kang M S, Park M H
机构信息
Department of Laboratory Medicine, Seoul Paik Hospital, Inje University College of Medicine, Seoul, Korea.
出版信息
Tissue Antigens. 2012 Feb;79(2):134-5. doi: 10.1111/j.1399-0039.2011.01793.x. Epub 2011 Oct 31.
Abstract
The new allele, HLA-A33:25, differs from A33:03:01 by one nucleotide substitution in exon 4 (c.778G>A) which results in an amino acid change at codon 236 [GCA→ACA (Ala>Thr)] in β2-microglobulin-binding domain.
摘要
新等位基因HLA - A33:25与A33:03:01在外显子4中存在一个核苷酸替换（c.778G>A），这导致β2 - 微球蛋白结合域中第236位密码子发生氨基酸变化[GCA→ACA（丙氨酸>苏氨酸）]。
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